Clinical Practice Guidelines (CPG) on EBMonFHIR
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: Mortality Outcome for Dexamethasone application - XML Representation

Active as of 2024-05-15

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<Evidence xmlns="http://hl7.org/fhir">
  <id value="DexamethasoneOutcomeMortality"/>
  <meta>
    <profile
             value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p><b>Generated Narrative: Evidence</b><a name="DexamethasoneOutcomeMortality"> </a><a name="hcDexamethasoneOutcomeMortality"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidence &quot;DexamethasoneOutcomeMortality&quot; </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-outcome-evidence-synthesis.html">Outcome Evidence Synthesis</a></p></div><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/Evidence/DexamethasoneOutcomeMortality</code></p><p><b>name</b>: ExampleOutcomeEvidence</p><p><b>status</b>: active</p><p><b>date</b>: 2024-05-15 06:48:35+0000</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td><a href="Citation-SystemicCorticosteroidsForTheTreatmentOfCOVID19.html">Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19</a> &quot;SystemicCorticosteroidsForTheTreatmentOfCOVID19&quot;</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href="Group-StudyCohortCorticosteroidsCOVID19.html">Group/StudyCohortCorticosteroidsCOVID19</a> &quot;StudyCohortCriteriaSystemicCorticosteroidsCOVID19&quot;</p><p><b>intended</b>: <a href="EvidenceVariable-StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19.html">EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</a> &quot;StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19&quot;</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: <a href="EvidenceVariable-OutcomeAllCauseMortality.html">EvidenceVariable/OutcomeAllCauseMortality</a> &quot;AllCauseMortality&quot;</p></blockquote><p><b>synthesisType</b>: not applicable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-synthesis-type.html">SynthesisType</a>#NotApplicable)</span></p><blockquote><p><b>statistic</b></p><p><b>description</b>: Relative effect of intervention vs. comparator</p><p><b>statisticType</b>: Relative Risk <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-statistic-type.html">StatisticStatisticType</a>#C93152)</span></p><p><b>quantity</b>: 0.89</p><h3>SampleSizes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>NumberOfStudies</b></td><td><b>NumberOfParticipants</b></td></tr><tr><td style="display: none">*</td><td>9</td><td>7930</td></tr></table><h3>AttributeEstimates</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>Confidence interval <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-attribute-estimate-type.html">StatisticAttribute Estimate Type</a>#C53324)</span></td><td>0.95</td><td>0.8-1</td></tr></table></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: Baseline risk/result in the comparison group</p><p><b>statisticType</b>: Incidence <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-statistic-type.html">StatisticStatisticType</a>#C16726)</span></p><p><b>quantity</b>: 245 1/1000<span style="background: LightGoldenRodYellow"> (Details: UCUM code 1/1000 = '1/1000')</span></p></blockquote></div>
  </text>
  <url
       value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/Evidence/DexamethasoneOutcomeMortality"/>
  <name value="ExampleOutcomeEvidence"/>
  <status value="active"/>
  <date value="2024-05-15T06:48:35+00:00"/>
  <relatedArtifact>
    <type value="citation"/>
    <resourceReference>🔗 
      <reference
                 value="Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19"/>
    </resourceReference>
  </relatedArtifact>
  <variableDefinition>
    <variableRole>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/variable-role"/>
        <code value="population"/>
      </coding>
    </variableRole>
    <observed>🔗 
      <reference value="Group/StudyCohortCorticosteroidsCOVID19"/>
    </observed>
    <intended>🔗 
      <reference
                 value="EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"/>
    </intended>
  </variableDefinition>
  <variableDefinition>
    <variableRole>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/variable-role"/>
        <code value="measuredVariable"/>
      </coding>
    </variableRole>
    <observed>🔗 
      <reference value="EvidenceVariable/OutcomeAllCauseMortality"/>
    </observed>
  </variableDefinition>
  <synthesisType>
    <coding>
      <system value="http://terminology.hl7.org/CodeSystem/synthesis-type"/>
      <code value="NotApplicable"/>
    </coding>
  </synthesisType>
  <statistic>
    <description value="Relative effect of intervention vs. comparator"/>
    <statisticType>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/statistic-type"/>
        <code value="C93152"/>
        <display value="Relative Risk"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="0.89"/>
    </quantity>
    <sampleSize>
      <numberOfStudies value="9"/>
      <numberOfParticipants value="7930"/>
    </sampleSize>
    <attributeEstimate>
      <type>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/attribute-estimate-type"/>
          <code value="C53324"/>
          <display value="Confidence interval"/>
        </coding>
      </type>
      <level value="0.95"/>
      <range>
        <low>
          <value value="0.8"/>
        </low>
        <high>
          <value value="1"/>
        </high>
      </range>
    </attributeEstimate>
  </statistic>
  <statistic>
    <description value="Baseline risk/result in the comparison group"/>
    <statisticType>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/statistic-type"/>
        <code value="C16726"/>
        <display value="Incidence"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="245"/>
      <system value="http://unitsofmeasure.org"/>
      <code value="1/1000"/>
    </quantity>
  </statistic>
</Evidence>