Mortality Outcome for Dexamethasone application - XML Representation - Clinical Practice Guidelines (CPG) on EBMonFHIR v1.0.2

Clinical Practice Guidelines (CPG) on EBMonFHIR
1.0.2 - qa-preview
This page is part of the CPG-on-EBMonFHIR Implementation Guide (1.0.2).
: Mortality Outcome for Dexamethasone application - XML Representation

Active as of 2024-10-21

<Evidence xmlns="http://hl7.org/fhir">
  <id value="DexamethasoneOutcomeMortality"/>
  <meta>
    <profile
             value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml"><p class="res-header-id"><b>Generated Narrative: Evidence DexamethasoneOutcomeMortality</b></p><a name="DexamethasoneOutcomeMortality"> </a><a name="hcDexamethasoneOutcomeMortality"> </a><a name="DexamethasoneOutcomeMortality-en-US"> </a><p><b>url</b>: <a href="Evidence-DexamethasoneOutcomeMortality.html">Evidence ExampleOutcomeEvidence</a></p><p><b>name</b>: ExampleOutcomeEvidence</p><p><b>status</b>: Active</p><p><b>date</b>: 2024-10-21 14:50:59+0000</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>Citation</td><td><a href="Citation-SystemicCorticosteroidsForTheTreatmentOfCOVID19.html">Citation SystemicCorticosteroidsForTheTreatmentOfCOVID19</a></td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/variable-role population}">population</span></p><p><b>observed</b>: <a href="Group-StudyCohortCorticosteroidsCOVID19.html">Group StudyCohortCriteriaSystemicCorticosteroidsCOVID19</a></p><p><b>intended</b>: <a href="EvidenceVariable-StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19.html">EvidenceVariable StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</a></p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/variable-role measuredVariable}">measured variable</span></p><p><b>observed</b>: <a href="EvidenceVariable-OutcomeAllCauseMortality.html">EvidenceVariable AllCauseMortality</a></p></blockquote><p><b>synthesisType</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/synthesis-type NotApplicable}">not applicable</span></p><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Relative effect of intervention vs. comparator</p>
</div><p><b>statisticType</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C93152}">Relative Risk</span></p><p><b>quantity</b>: 0.89</p><h3>SampleSizes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>NumberOfStudies</b></td><td><b>NumberOfParticipants</b></td></tr><tr><td style="display: none">*</td><td>9</td><td>7930</td></tr></table><h3>AttributeEstimates</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td><span title="Codes:{http://terminology.hl7.org/CodeSystem/attribute-estimate-type C53324}">Confidence interval</span></td><td>0.95</td><td>0.8-1</td></tr></table></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: </p><div><p>Baseline risk/result in the comparison group</p>
</div><p><b>statisticType</b>: <span title="Codes:{http://terminology.hl7.org/CodeSystem/statistic-type C16726}">Incidence</span></p><p><b>quantity</b>: 245 1/1000<span style="background: LightGoldenRodYellow"> (Details: UCUM  code1/1000 = '1/1000')</span></p></blockquote></div>
  </text>
  <url
       value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/Evidence/DexamethasoneOutcomeMortality"/>
  <name value="ExampleOutcomeEvidence"/>
  <status value="active"/>
  <date value="2024-10-21T14:50:59+00:00"/>
  <relatedArtifact>
    <type value="citation"/>
    <resourceReference>🔗 
      <reference
                 value="Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19"/>
    </resourceReference>
  </relatedArtifact>
  <variableDefinition>
    <variableRole>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/variable-role"/>
        <code value="population"/>
      </coding>
    </variableRole>
    <observed>🔗 
      <reference value="Group/StudyCohortCorticosteroidsCOVID19"/>
    </observed>
    <intended>🔗 
      <reference
                 value="EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"/>
    </intended>
  </variableDefinition>
  <variableDefinition>
    <variableRole>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/variable-role"/>
        <code value="measuredVariable"/>
      </coding>
    </variableRole>
    <observed>🔗 
      <reference value="EvidenceVariable/OutcomeAllCauseMortality"/>
    </observed>
  </variableDefinition>
  <synthesisType>
    <coding>
      <system value="http://terminology.hl7.org/CodeSystem/synthesis-type"/>
      <code value="NotApplicable"/>
    </coding>
  </synthesisType>
  <statistic>
    <description value="Relative effect of intervention vs. comparator"/>
    <statisticType>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/statistic-type"/>
        <code value="C93152"/>
        <display value="Relative Risk"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="0.89"/>
    </quantity>
    <sampleSize>
      <numberOfStudies value="9"/>
      <numberOfParticipants value="7930"/>
    </sampleSize>
    <attributeEstimate>
      <type>
        <coding>
          <system
                  value="http://terminology.hl7.org/CodeSystem/attribute-estimate-type"/>
          <code value="C53324"/>
          <display value="Confidence interval"/>
        </coding>
      </type>
      <level value="0.95"/>
      <range>
        <low>
          <value value="0.8"/>
        </low>
        <high>
          <value value="1"/>
        </high>
      </range>
    </attributeEstimate>
  </statistic>
  <statistic>
    <description value="Baseline risk/result in the comparison group"/>
    <statisticType>
      <coding>
        <system value="http://terminology.hl7.org/CodeSystem/statistic-type"/>
        <code value="C16726"/>
        <display value="Incidence"/>
      </coding>
    </statisticType>
    <quantity>
      <value value="245"/>
      <system value="http://unitsofmeasure.org"/>
      <code value="1/1000"/>
    </quantity>
  </statistic>
</Evidence>