Clinical Practice Guidelines (CPG) on EBMonFHIR
0.8.0-snapshot - ci-build
Clinical Practice Guidelines (CPG) on EBMonFHIR - Local Development build (v0.8.0-snapshot) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Composition_COVID19IntensiveCareTreatmentGuideline"> </a><p><b>Generated Narrative: Composition</b><a name="COVID19IntensiveCareTreatmentGuideline"> </a><a name="hcCOVID19IntensiveCareTreatmentGuideline"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceComposition "COVID19IntensiveCareTreatmentGuideline" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-guideline.html">Clinical Practice Guideline</a></p></div><p><b>identifier</b>: Resource identifier/113-001</p><p><b>version</b>: 7.0</p><p><b>status</b>: final</p><p><b>type</b>: Guidelines <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline; #e07eN1w1Rwswg4)</span></p><p><b>category</b>: Evidence- and consensus-based guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-guideline-stage-classification.html">Guideline Stage Classification</a>#S3)</span></p><p><b>date</b>: 2022-03-01</p><p><b>author</b>: <a href="Organization-AWMFOrganization.html">Organization/AWMFOrganization</a> "Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) e.V."</p><p><b>title</b>: Empfehlungen zur stationären Therapie von Patienten mit COVID-19 - Living Guideline</p><h3>RelatesTos</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td>See on this page: Citation/COVID19IntensiveCareTreatmentGuidelineCitation</td></tr></table></div>
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<focus>🔗
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<div xmlns="http://www.w3.org/1999/xhtml"><strong>Systemische Steroide:</strong> Bei Patienten mit COVID-19- und Sauerstoff-Bedarf (Niedrigfluss-Sauerstoff-Insufflation, High-Flow Nasal Cannula, Nichtinvasive Beatmung/CPAP, invasive Beatmung) soll eine Therapie mit systemischen Kortikosteroiden erfolgen. Die Therapie sollte mit 6 mg Dexamethason p.o. oder i.v. über zehn Tage erfolgen.</div>
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<div xmlns="http://www.w3.org/1999/xhtml"><strong>Systemische Steroide:</strong> Bei Patienten mit moderater Erkrankung (hospitalisiert ohne Notwendigkeit von Niedrigfluss-Sauerstoff-Insufflation) soll keine Therapie mit systemischen Kortikosteroiden erfolgen.</div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Citation_COVID19IntensiveCareTreatmentGuidelineCitation"> </a><p><b>Generated Narrative: Citation</b><a name="COVID19IntensiveCareTreatmentGuidelineCitation"> </a><a name="hcCOVID19IntensiveCareTreatmentGuidelineCitation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceCitation "COVID19IntensiveCareTreatmentGuidelineCitation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-guideline-citation.html">Guideline Citation</a></p></div><p><b>name</b>: COVID19_Intensive_Care_Treatment_Guideline</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://www.awmf.org/</code>/113-001</p><h3>Versions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Value</b></td></tr><tr><td style="display: none">*</td><td>7.0</td></tr></table><p><b>currentState</b>: Active <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html">Cited Artifact Status Type</a>#active)</span></p><h3>Titles</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Text</b></td></tr><tr><td style="display: none">*</td><td>S3-Leitlinie Stationäre Therapie von COVID-19 Patienten</td></tr></table><h3>WebLocations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Url</b></td></tr><tr><td style="display: none">*</td><td><a href="https://www.awmf.org/leitlinien/detail/ll/113-001.html">https://www.awmf.org/leitlinien/detail/ll/113-001.html</a></td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style="display: none">*</td><td>Publication Type <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline)</span></td></tr></table></blockquote></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_COVID19DexamethasoneApplication"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="COVID19DexamethasoneApplication"> </a><a name="hcCOVID19DexamethasoneApplication"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourcePlanDefinition "COVID19DexamethasoneApplication" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation.html">Recommendation</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: One or More <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#one-or-more)</span></p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation</code></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href="EvidenceVariable-PopulationCOVID19Ventilated.html">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Application of Dexamethasone for ventilated patients only</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>justification</td><td>Recommendation rating <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#recommendation-rating)</span></td><td>See on this page: ArtifactAssessment/DexamethasoneRecommendationJustification</td></tr><tr><td style="display: none">*</td><td>citation</td><td>Clinical practice guideline recommendation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#guideline-recommendation)</span></td><td>See on this page: Citation/DexamethasoneRecommendationCitation</td></tr><tr><td style="display: none">*</td><td>citation</td><td>Clinical practice guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline)</span></td><td>See on this page: Citation/COVID19IntensiveCareTreatmentGuidelineCitation</td></tr></table><blockquote><p><b>action</b></p><p><b>title</b>: Dexamethasone Application</p><p><b>description</b>: Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p><p><b>code</b>: Guideline-based Care <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href="PlanDefinition-COVID19VentilatedPatientsDexamethasoneApplicationPlan.html">Dexamethasone Application in ventilated COVID-19 patients</a></p></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: No Dexamethasone Application</p><p><b>description</b>: No Dexamethasone Application for non-ventilated COVID-19 patients</p><p><b>code</b>: Guideline-based Care <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href="PlanDefinition-COVID19NonVentilatedPatientsDexamethasoneApplicationPlan.html">No Dexamethasone Application for non-ventilated COVID-19 patients</a></p></blockquote></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_COVID19VentilatedPatientsDexamethasoneApplicationPlan"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="COVID19VentilatedPatientsDexamethasoneApplicationPlan"> </a><a name="hcCOVID19VentilatedPatientsDexamethasoneApplicationPlan"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourcePlanDefinition "COVID19VentilatedPatientsDexamethasoneApplicationPlan" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-plan.html">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href="PlanDefinition-COVID19DexamethasoneApplication.html">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: Exactly <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#exactly)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 1</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan</code></p><p><b>version</b>: 4.0</p><p><b>name</b>: Dexamethasone_Application</p><p><b>title</b>: Dexamethasone Application in ventilated COVID-19 patients</p><p><b>type</b>: ECA Rule <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#eca-rule)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href="EvidenceVariable-PopulationCOVID19Ventilated.html">Population_COVID19_Ventilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients</p><blockquote><p><b>action</b></p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>definition</b>: <a href="Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html">DexamethasoneApplicationActionOral</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>definition</b>: <a href="Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html">DexamethasoneApplicationActionIntravenous</a></p></blockquote></div>
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</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-ventilated-patients-dexamethasone-application-plan"/>
<version value="4.0"/>
<name value="Dexamethasone_Application"/>
<title
value="Dexamethasone Application in ventilated COVID-19 patients"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="eca-rule"/>
</coding>
</type>
<status value="active"/>
<experimental value="true"/>
<subjectCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated"/>
<date value="2021-12-12"/>
<publisher value="CPGonEBMonFHIR"/>
<description
value="Application of Dexamethasone: 6 mg once per day for 10 days p.o. or i.v. for ventilated COVID-19 patients"/>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<definitionCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral"/>
</action>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<definitionCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous"/>
</action>
</PlanDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-plan-non-ventilated-patients"/>
<resource>
<PlanDefinition>
<id value="COVID19NonVentilatedPatientsDexamethasoneApplicationPlan"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_COVID19NonVentilatedPatientsDexamethasoneApplicationPlan"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="COVID19NonVentilatedPatientsDexamethasoneApplicationPlan"> </a><a name="hcCOVID19NonVentilatedPatientsDexamethasoneApplicationPlan"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourcePlanDefinition "COVID19NonVentilatedPatientsDexamethasoneApplicationPlan" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-plan.html">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href="PlanDefinition-COVID19DexamethasoneApplication.html">Dexamethasone Application</a></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: Exactly <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#exactly)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 1</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan</code></p><p><b>version</b>: 4.0</p><p><b>name</b>: No_Dexamethasone_Application</p><p><b>title</b>: No Dexamethasone Application for non-ventilated COVID-19 patients</p><p><b>type</b>: ECA Rule <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#eca-rule)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href="EvidenceVariable-PopulationCOVID19NonVentilated.html">Population_COVID19_NonVentilated</a></p><p><b>date</b>: 2021-12-12</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: No Dexamethasone Application for non-ventilated COVID19 patients</p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>Definition[x]</b></td></tr><tr><td style="display: none">*</td><td>Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></td><td><a href="Bundle-COVID19IntensiveCareTreatmentGuidelineBundle.html">NoDexamethasoneApplicationActivity</a></td></tr></table></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="computable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-partOf">
<valueCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-dexamethasone-recommendation"/>
</extension>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method">
<extension url="method">
<valueCodeableConcept>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"/>
<code value="exactly"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="threshold">
<valuePositiveInt value="1"/>
</extension>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/covid19-non-ventilated-patients-no-dexamethasone-application-plan"/>
<version value="4.0"/>
<name value="No_Dexamethasone_Application"/>
<title
value="No Dexamethasone Application for non-ventilated COVID-19 patients"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="eca-rule"/>
</coding>
</type>
<status value="active"/>
<experimental value="true"/>
<subjectCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated"/>
<date value="2021-12-12"/>
<publisher value="CPGonEBMonFHIR"/>
<description
value="No Dexamethasone Application for non-ventilated COVID19 patients"/>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<definitionCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application"/>
</action>
</PlanDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-oral"/>
<resource>
<ActivityDefinition>
<id value="DexamethasoneApplicationActionOral"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ActivityDefinition_DexamethasoneApplicationActionOral"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name="DexamethasoneApplicationActionOral"> </a><a name="hcDexamethasoneApplicationActionOral"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceActivityDefinition "DexamethasoneApplicationActionOral" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-drug-administration-action.html">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionOral</p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: Patient <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-fhir-types.html">All FHIR Types</a>#Patient)</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Application of Dexamethasone: 6 mg once per day for 10 days (oral route)</p><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>product</b>: Dexamethasone (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#372584003; atc#C05AA09 "Dexamethason")</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10 times, Duration 10days , Once per 1 days</p><p><b>route</b>: Oral route <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="computable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-oral"/>
<version value="1.0"/>
<name value="DexamethasoneApplicationActionOral"/>
<status value="active"/>
<experimental value="true"/>
<subjectCodeableConcept>
<coding>
<system value="http://hl7.org/fhir/fhir-types"/>
<code value="Patient"/>
</coding>
</subjectCodeableConcept>
<publisher value="CPGonEBMonFHIR"/>
<description
value="Application of Dexamethasone: 6 mg once per day for 10 days (oral route)"/>
<kind value="MedicationRequest"/>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<productCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="372584003"/>
<display value="Dexamethasone (substance)"/>
</coding>
<coding>
<system value="http://fhir.de/CodeSystem/bfarm/atc"/>
<code value="C05AA09"/>
<display value="Dexamethason"/>
</coding>
</productCodeableConcept>
<dosage>
<timing>
<repeat>
<count value="10"/>
<duration value="10"/>
<durationUnit value="d"/>
<frequency value="1"/>
<period value="1"/>
<periodUnit value="d"/>
</repeat>
</timing>
<route>
<coding>
<system value="http://snomed.info/sct"/>
<code value="26643006"/>
<display value="Oral route"/>
</coding>
</route>
<doseAndRate>
<doseQuantity>
<value value="6"/>
<unit value="mg"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg"/>
</doseQuantity>
<rateQuantity>
<value value="1"/>
<unit value="/d"/>
<system value="http://unitsofmeasure.org"/>
<code value="/d"/>
</rateQuantity>
</doseAndRate>
</dosage>
</ActivityDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-intravenous"/>
<resource>
<ActivityDefinition>
<id value="DexamethasoneApplicationActionIntravenous"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ActivityDefinition_DexamethasoneApplicationActionIntravenous"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name="DexamethasoneApplicationActionIntravenous"> </a><a name="hcDexamethasoneApplicationActionIntravenous"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceActivityDefinition "DexamethasoneApplicationActionIntravenous" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-drug-administration-action.html">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: DexamethasoneApplicationActionIntravenous</p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: Patient <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-fhir-types.html">All FHIR Types</a>#Patient)</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)</p><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>product</b>: Dexamethasone (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#372584003; atc#C05AA09 "Dexamethason")</span></p><blockquote><p><b>dosage</b></p><p><b>timing</b>: Count 10 times, Duration 10days , Once per 1 days</p><p><b>route</b>: Intravenous route <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#47625008)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="computable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/dexamethasone-application-intravenous"/>
<version value="1.0"/>
<name value="DexamethasoneApplicationActionIntravenous"/>
<status value="active"/>
<experimental value="true"/>
<subjectCodeableConcept>
<coding>
<system value="http://hl7.org/fhir/fhir-types"/>
<code value="Patient"/>
</coding>
</subjectCodeableConcept>
<publisher value="CPGonEBMonFHIR"/>
<description
value="Application of Dexamethasone: 6 mg once per day for 10 days (intravenous route)"/>
<kind value="MedicationRequest"/>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<productCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="372584003"/>
<display value="Dexamethasone (substance)"/>
</coding>
<coding>
<system value="http://fhir.de/CodeSystem/bfarm/atc"/>
<code value="C05AA09"/>
<display value="Dexamethason"/>
</coding>
</productCodeableConcept>
<dosage>
<timing>
<repeat>
<count value="10"/>
<duration value="10"/>
<durationUnit value="d"/>
<frequency value="1"/>
<period value="1"/>
<periodUnit value="d"/>
</repeat>
</timing>
<route>
<coding>
<system value="http://snomed.info/sct"/>
<code value="47625008"/>
<display value="Intravenous route"/>
</coding>
</route>
<doseAndRate>
<doseQuantity>
<value value="6"/>
<unit value="mg"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg"/>
</doseQuantity>
<rateQuantity>
<value value="1"/>
<unit value="/d"/>
<system value="http://unitsofmeasure.org"/>
<code value="/d"/>
</rateQuantity>
</doseAndRate>
</dosage>
</ActivityDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-action-no-application"/>
<resource>
<ActivityDefinition>
<id value="NoDexamethasoneApplication"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ActivityDefinition_NoDexamethasoneApplication"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name="NoDexamethasoneApplication"> </a><a name="hcNoDexamethasoneApplication"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceActivityDefinition "NoDexamethasoneApplication" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-drug-administration-action.html">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: NoDexamethasoneApplicationActivity</p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: Patient <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-fhir-types.html">All FHIR Types</a>#Patient)</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: No Application of Dexamethasone</p><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>doNotPerform</b>: true</p><p><b>product</b>: Dexamethasone (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#372584003; atc#C05AA09 "Dexamethason")</span></p></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="computable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/no-dexamethasone-application"/>
<version value="1.0"/>
<name value="NoDexamethasoneApplicationActivity"/>
<status value="active"/>
<experimental value="true"/>
<subjectCodeableConcept>
<coding>
<system value="http://hl7.org/fhir/fhir-types"/>
<code value="Patient"/>
</coding>
</subjectCodeableConcept>
<publisher value="CPGonEBMonFHIR"/>
<description value="No Application of Dexamethasone"/>
<kind value="MedicationRequest"/>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<doNotPerform value="true"/>
<productCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="372584003"/>
<display value="Dexamethasone (substance)"/>
</coding>
<coding>
<system value="http://fhir.de/CodeSystem/bfarm/atc"/>
<code value="C05AA09"/>
<display value="Dexamethason"/>
</coding>
</productCodeableConcept>
</ActivityDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/recommendation-citation"/>
<resource>
<Citation>
<id value="DexamethasoneRecommendationCitation"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Citation_DexamethasoneRecommendationCitation"> </a><p><b>Generated Narrative: Citation</b><a name="DexamethasoneRecommendationCitation"> </a><a name="hcDexamethasoneRecommendationCitation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceCitation "DexamethasoneRecommendationCitation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-citation.html">Recommendation Citation</a></p></div><p><b>name</b>: DexamethasoneRecommendationCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: <code>https://api.magicapp.org/api/v1/recommendations</code>/98398</p><h3>Versions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Value</b></td></tr><tr><td style="display: none">*</td><td>v4.0</td></tr></table><p><b>currentState</b>: Active <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html">Cited Artifact Status Type</a>#active)</span></p><h3>Titles</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Text</b></td></tr><tr><td style="display: none">*</td><td>Steroide</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style="display: none">*</td><td>Publication Type <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline recommendation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#guideline-recommendation)</span></td></tr></table></blockquote></div>
</text>
<name value="DexamethasoneRecommendationCitation"/>
<status value="active"/>
<citedArtifact>
<identifier>
<system value="https://api.magicapp.org/api/v1/recommendations"/>
<value value="98398"/>
</identifier>
<version>
<value value="v4.0"/>
</version>
<currentState>
<coding>
<system value="http://hl7.org/fhir/cited-artifact-status-type"/>
<code value="active"/>
<display value="Active"/>
</coding>
</currentState>
<title>
<text value="Steroide"/>
</title>
<classification>
<type>
<coding>
<system
value="http://hl7.org/fhir/cited-artifact-classification-type"/>
<code value="publication-type"/>
<display value="Publication Type"/>
</coding>
</type>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="guideline-recommendation"/>
<display value="Clinical practice guideline recommendation"/>
</coding>
</classifier>
</classification>
</citedArtifact>
</Citation>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-ventilated"/>
<resource>
<EvidenceVariable>
<id value="PopulationCOVID19Ventilated"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_PopulationCOVID19Ventilated"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="PopulationCOVID19Ventilated"> </a><a name="hcPopulationCOVID19Ventilated"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "PopulationCOVID19Ventilated" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-eligibility-criteria.html">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated</code></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/Ventilated</p><p><b>name</b>: Population_COVID19_Ventilated</p><p><b>status</b>: active</p><p><b>description</b>: Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: any-of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote></blockquote></blockquote></div>
</text>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_Ventilated"/>
<identifier>
<system value="https://www.ceosys.de"/>
<value value="Ventilated"/>
</identifier>
<name value="Population_COVID19_Ventilated"/>
<status value="active"/>
<description
value="Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, Ventilated"/>
<characteristic>
<linkId value="covid19"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="840539006"/>
<display
value="Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
</characteristic>
<characteristic>
<exclude value="false"/>
<definitionByCombination>
<code value="any-of"/>
<characteristic>
<linkId value="oxy-administration-nasal-cannula"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="371907003"/>
<display
value="Oxygen administration by nasal cannula (procedure)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
<characteristic>
<linkId value="noninvasive-ventilation"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="428311008"/>
<display
value="Non-invasive ventilation (regime/therapy)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
<characteristic>
<linkId value="artificial-respiration"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="40617009"/>
<display value="Artificial ventilation (regime/therapy)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
</definitionByCombination>
</characteristic>
</EvidenceVariable>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/evidence-variable-non-ventilated"/>
<resource>
<EvidenceVariable>
<id value="PopulationCOVID19NonVentilated"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_PopulationCOVID19NonVentilated"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="PopulationCOVID19NonVentilated"> </a><a name="hcPopulationCOVID19NonVentilated"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "PopulationCOVID19NonVentilated" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-eligibility-criteria.html">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated</code></p><p><b>identifier</b>: <code>https://www.ceosys.de</code>/NonVentilated</p><p><b>name</b>: Population_COVID19_NonVentilated</p><p><b>status</b>: active</p><p><b>description</b>: Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: covid19</p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: true</p><blockquote><p><b>definitionByCombination</b></p><p><b>code</b>: any-of</p><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: oxy-administration-nasal-cannula</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: noninvasive-ventilation</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote><blockquote><p><b>characteristic</b></p><p><b>linkId</b>: artificial-respiration</p><p><b>exclude</b>: false</p><blockquote><p><b>definitionByTypeAndValue</b></p></blockquote><blockquote><p><b>timeFromEvent</b></p></blockquote></blockquote></blockquote></blockquote></div>
</text>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/population/Population_COVID19_NonVentilated"/>
<identifier>
<system value="https://www.ceosys.de"/>
<value value="NonVentilated"/>
</identifier>
<name value="Population_COVID19_NonVentilated"/>
<status value="active"/>
<description
value="Population for guideline from https://app.magicapp.org/#/guidelines / 5691 with characteristics: COVID-19, not ventilated"/>
<characteristic>
<linkId value="covid19"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="840539006"/>
<display
value="Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
</characteristic>
<characteristic>
<exclude value="true"/>
<definitionByCombination>
<code value="any-of"/>
<characteristic>
<linkId value="oxy-administration-nasal-cannula"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="371907003"/>
<display
value="Oxygen administration by nasal cannula (procedure)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
<characteristic>
<linkId value="noninvasive-ventilation"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="428311008"/>
<display
value="Non-invasive ventilation (regime/therapy)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
<characteristic>
<linkId value="artificial-respiration"/>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="71388002"/>
<display value="Procedure (procedure)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="40617009"/>
<display value="Artificial ventilation (regime/therapy)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
<timeFromEvent>
<eventId value="covid19"/>
<quantity>
<value value="0"/>
<system value="http://unitsofmeasure.org"/>
<code value="d"/>
</quantity>
</timeFromEvent>
</characteristic>
</definitionByCombination>
</characteristic>
</EvidenceVariable>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/covid19-intensive-care-treatment/dexamethasone/rating-outcome-mortality"/>
<resource>
<ArtifactAssessment>
<id value="DexamethasoneRatingOutcomeMortality"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/certainty-of-evidence-rating"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ArtifactAssessment_DexamethasoneRatingOutcomeMortality"> </a><p><b>Generated Narrative: ArtifactAssessment</b><a name="DexamethasoneRatingOutcomeMortality"> </a><a name="hcDexamethasoneRatingOutcomeMortality"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceArtifactAssessment "DexamethasoneRatingOutcomeMortality" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-certainty-of-evidence-rating.html">Certainty of Evidence Rating</a></p></div><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: See on this page: Evidence/DexamethasoneOutcomeMortality</p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Overall certainty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Overall)</span></p><p><b>classifier</b>: Moderate quality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#moderate)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Clinical Importance <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-importance)</span></p><p><b>classifier</b>: Critical <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-clinical-importance.html">Clinical Importance of Outcome</a>#9)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Risk of bias <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#RiskOfBias)</span></p><p><b>classifier</b>: serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#serious-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Inconsistency <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Inconsistency)</span></p><p><b>classifier</b>: no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#no-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Indirectness <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Indirectness)</span></p><p><b>classifier</b>: no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#no-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Imprecision <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Imprecision)</span></p><p><b>classifier</b>: no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#no-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Publication bias <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#PublicationBias)</span></p><p><b>classifier</b>: no serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#no-concern)</span></p></blockquote></div>
</text>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version">
<valueString value="v4.0"/>
</extension>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status">
<valueCode value="active"/>
</extension>
<date value="2020-01-03"/>
<artifactReference>🔗
<reference value="Evidence/DexamethasoneOutcomeMortality"/>
</artifactReference>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Overall"/>
<display value="Overall certainty"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="moderate"/>
<display value="Moderate quality"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="clinical-importance"/>
<display value="Clinical Importance"/>
</coding>
</type>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-clinical-importance"/>
<code value="9"/>
<display value="Critical"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="RiskOfBias"/>
<display value="Risk of bias"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Inconsistency"/>
<display value="Inconsistency"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Evidence_DexamethasoneOutcomeMortality"> </a><p><b>Generated Narrative: Evidence</b><a name="DexamethasoneOutcomeMortality"> </a><a name="hcDexamethasoneOutcomeMortality"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidence "DexamethasoneOutcomeMortality" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-outcome-evidence-synthesis.html">Outcome Evidence Synthesis</a></p></div><p><b>name</b>: ExampleOutcomeEvidence</p><p><b>status</b>: active</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td>See on this page: Citation/SystemicCorticosteroidsForTheTreatmentOfCOVID19</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href="Group-StudyCohortCorticosteroidsCOVID19.html">Group/StudyCohortCorticosteroidsCOVID19</a> "StudyCohortCriteriaSystemicCorticosteroidsCOVID19"</p><p><b>intended</b>: See on this page: EvidenceVariable/StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: See on this page: EvidenceVariable/OutcomeAllCauseMortality</p></blockquote><p><b>synthesisType</b>: not applicable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-synthesis-type.html">SynthesisType</a>#NotApplicable)</span></p><blockquote><p><b>statistic</b></p><p><b>description</b>: Relative effect of intervention vs. comparator</p><p><b>statisticType</b>: Relative Risk <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-statistic-type.html">StatisticStatisticType</a>#C93152)</span></p><p><b>quantity</b>: 0.89</p><h3>SampleSizes</h3><table class="grid"><tr><td style="display: none">-</td><td><b>NumberOfStudies</b></td><td><b>NumberOfParticipants</b></td></tr><tr><td style="display: none">*</td><td>9</td><td>7930</td></tr></table><h3>AttributeEstimates</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>Confidence interval <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-attribute-estimate-type.html">StatisticAttribute Estimate Type</a>#C53324)</span></td><td>0.95</td><td>0.8-1</td></tr></table></blockquote><blockquote><p><b>statistic</b></p><p><b>description</b>: Baseline risk/result in the comparison group</p><p><b>statisticType</b>: Incidence <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-statistic-type.html">StatisticStatisticType</a>#C16726)</span></p><p><b>quantity</b>: 245 1/1000<span style="background: LightGoldenRodYellow"> (Details: UCUM code 1/1000 = '1/1000')</span></p></blockquote></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"> </a><a name="hcStudyEligibilityCriteriaSystemicCorticosteroidsCOVID19"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-study-eligibility-criteria.html">Study Eligibility Criteria</a></p></div><p><b>name</b>: StudyEligibilityCriteriaSystemicCorticosteroidsCOVID19</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_OutcomeAllCauseMortality"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="OutcomeAllCauseMortality"> </a><a name="hcOutcomeAllCauseMortality"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "OutcomeAllCauseMortality" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-outcome-definition.html">Outcome Definition</a></p></div><p><b>name</b>: AllCauseMortality</p><p><b>status</b>: active</p><h3>Characteristics</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Exclude</b></td><td><b>DefinitionCodeableConcept</b></td></tr><tr><td style="display: none">*</td><td>false</td><td>Mortality rate (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#409651001)</span></td></tr></table><p><b>handling</b>: dichotomous</p></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="ArtifactAssessment_DexamethasoneRecommendationJustification"> </a><p><b>Generated Narrative: ArtifactAssessment</b><a name="DexamethasoneRecommendationJustification"> </a><a name="hcDexamethasoneRecommendationJustification"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceArtifactAssessment "DexamethasoneRecommendationJustification" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-justification.html">Recommendation Justification</a></p></div><p><b>ArtifactAssessment Version</b>: v4.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: See on this page: PlanDefinition/COVID19VentilatedPatientsDexamethasoneApplicationPlan</p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Strength of recommendation <span style="background: LightGoldenRodYellow; 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