Clinical Practice Guidelines (CPG) on EBMonFHIR
0.8.0-snapshot - ci-build

Clinical Practice Guidelines (CPG) on EBMonFHIR - Local Development build (v0.8.0-snapshot) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions

: Guideline Recommendation Example - JSON Representation

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{
  "resourceType" : "Bundle",
  "id" : "GuidelineRecommendationExample",
  "meta" : {
    "profile" : [
      🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-bundle"
    ]
  },
  "type" : "collection",
  "entry" : [
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example",
      "resource" : {
        "resourceType" : "Composition",
        "id" : "GuidelineExample",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Composition_GuidelineExample\"> </a><p><b>Generated Narrative: Composition</b><a name=\"GuidelineExample\"> </a><a name=\"hcGuidelineExample\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceComposition &quot;GuidelineExample&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-guideline.html\">Clinical Practice Guideline</a></p></div><p><b>identifier</b>: Resource identifier/guideline example</p><p><b>version</b>: 0.1.0</p><p><b>status</b>: final</p><p><b>type</b>: Guidelines <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#clinical-practice-guideline; #e07eN1w1Rwswg4)</span></p><p><b>category</b>: Evidence- and consensus-based guideline <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-guideline-stage-classification.html\">Guideline Stage Classification</a>#S3)</span></p><p><b>date</b>: 2022-01-28</p><p><b>author</b>: <a href=\"Organization-ExampleOrganization.html\">Organization/ExampleOrganization</a> &quot;Example Organization&quot;</p><p><b>title</b>: Example Guideline</p><h3>RelatesTos</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>citation</td><td>See on this page: Citation/ExampleGuidelineCitation</td></tr></table></div>"
        },
        "identifier" : [
          {
            "type" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/v2-0203",
                  "code" : "RI",
                  "display" : "Resource identifier"
                }
              ]
            },
            "system" : "https://www.ceosys.de",
            "value" : "guideline example"
          }
        ],
        "version" : "0.1.0",
        "status" : "final",
        "type" : {
          "coding" : [
            {
              "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
              "code" : "clinical-practice-guideline"
            },
            {
              "system" : "https://data.cochrane.org/concepts/",
              "code" : "e07eN1w1Rwswg4",
              "display" : "Guidelines"
            }
          ]
        },
        "category" : [
          {
            "coding" : [
              {
                "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-guideline-stage-classification",
                "code" : "S3",
                "display" : "Evidence- and consensus-based guideline"
              }
            ]
          }
        ],
        "date" : "2022-01-28",
        "author" : [
          {
            🔗 "reference" : "Organization/ExampleOrganization"
          }
        ],
        "title" : "Example Guideline",
        "relatesTo" : [
          {
            "type" : "citation",
            "resourceReference" : {
              🔗 "reference" : "Citation/ExampleGuidelineCitation"
            }
          }
        ],
        "section" : [
          {
            "title" : "Example Guideline Recommendation",
            "code" : {
              "coding" : [
                {
                  "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                  "code" : "guideline-recommendation",
                  "display" : "Clinical practice guideline recommendation"
                }
              ]
            },
            "focus" : {
              🔗 "reference" : "PlanDefinition/ExampleRecommendation"
            },
            "text" : {
              "status" : "generated",
              "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\">This is an example guideline recommendation.</div>"
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/citation",
      "resource" : {
        "resourceType" : "Citation",
        "id" : "ExampleGuidelineCitation",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/guideline-citation"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_ExampleGuidelineCitation\"> </a><p><b>Generated Narrative: Citation</b><a name=\"ExampleGuidelineCitation\"> </a><a name=\"hcExampleGuidelineCitation\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceCitation &quot;ExampleGuidelineCitation&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-guideline-citation.html\">Guideline Citation</a></p></div><p><b>name</b>: ExampleGuidelineCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>1.0-alpha1</td></tr></table><p><b>currentState</b>: Archived <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html\">Cited Artifact Status Type</a>#archived)</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td>Example Citation</td></tr></table><h3>WebLocations</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Url</b></td></tr><tr><td style=\"display: none\">*</td><td><a href=\"https://example.com/guideline/exampleIdentifier\">https://example.com/guideline/exampleIdentifier</a></td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>Publication Type <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#clinical-practice-guideline)</span></td></tr></table></blockquote></div>"
        },
        "name" : "ExampleGuidelineCitation",
        "status" : "active",
        "citedArtifact" : {
          "identifier" : [
            {
              "value" : "ceoysy/exampleIdentifier"
            }
          ],
          "version" : {
            "value" : "1.0-alpha1"
          },
          "currentState" : [
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/cited-artifact-status-type",
                  "code" : "archived",
                  "display" : "Archived"
                }
              ]
            }
          ],
          "title" : [
            {
              "text" : "Example Citation"
            }
          ],
          "webLocation" : [
            {
              "url" : "https://example.com/guideline/exampleIdentifier"
            }
          ],
          "classification" : [
            {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/cited-artifact-classification-type",
                    "code" : "publication-type",
                    "display" : "Publication Type"
                  }
                ]
              },
              "classifier" : [
                {
                  "coding" : [
                    {
                      "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                      "code" : "clinical-practice-guideline",
                      "display" : "Clinical practice guideline"
                    }
                  ]
                }
              ]
            }
          ]
        }
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation",
      "resource" : {
        "resourceType" : "PlanDefinition",
        "id" : "ExampleRecommendation",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_ExampleRecommendation\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"ExampleRecommendation\"> </a><a name=\"hcExampleRecommendation\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourcePlanDefinition &quot;ExampleRecommendation&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation.html\">Recommendation</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: At Least <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-action-combination-method.html\">Action Combination Method</a>#at-least)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 2</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: Recommendation</p><p><b>title</b>: Recommendation</p><p><b>type</b>: Workflow Definition <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#workflow-definition)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>date</b>: 2022-02-14</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Example Recommendation</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>justification</td><td>Recommendation rating <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#recommendation-rating)</span></td><td>See on this page: ArtifactAssessment/ExampleRecommendationJustification</td></tr><tr><td style=\"display: none\">*</td><td>citation</td><td>Clinical practice guideline recommendation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#guideline-recommendation)</span></td><td>See on this page: Citation/ExampleRecommendationCitation</td></tr><tr><td style=\"display: none\">*</td><td>citation</td><td>Clinical practice guideline <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#clinical-practice-guideline)</span></td><td>See on this page: Citation/ExampleGuidelineCitation</td></tr></table><blockquote><p><b>action</b></p><p><b>title</b>: example recommendation</p><p><b>description</b>: Example recommendation</p><p><b>code</b>: Guideline-based Care <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html\">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href=\"PlanDefinition-ExampleRecommendationPlan.html\">Recommendation Plan</a></p></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: example recommendation</p><p><b>description</b>: Example recommendation</p><p><b>code</b>: Guideline-based Care <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html\">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href=\"PlanDefinition-ExampleRecommendationPlan.html\">Recommendation Plan</a></p></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
            "valueCode" : "computable"
          },
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
            "valueCode" : "structured"
          },
          {
            "extension" : [
              {
                "url" : "method",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method",
                      "code" : "at-least"
                    }
                  ]
                }
              },
              {
                "url" : "threshold",
                "valuePositiveInt" : 2
              }
            ],
            "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"
          }
        ],
        "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation",
        "version" : "1.0",
        "name" : "Recommendation",
        "title" : "Recommendation",
        "type" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
              "code" : "workflow-definition"
            }
          ]
        },
        "status" : "active",
        "experimental" : true,
        "date" : "2022-02-14",
        "publisher" : "CPGonEBMonFHIR",
        "description" : "Example Recommendation",
        "relatedArtifact" : [
          {
            "type" : "justification",
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                    "code" : "recommendation-rating",
                    "display" : "Recommendation rating"
                  }
                ]
              }
            ],
            "resourceReference" : {
              🔗 "reference" : "ArtifactAssessment/ExampleRecommendationJustification"
            }
          },
          {
            "type" : "citation",
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                    "code" : "guideline-recommendation",
                    "display" : "Clinical practice guideline recommendation"
                  }
                ]
              }
            ],
            "resourceReference" : {
              🔗 "reference" : "Citation/ExampleRecommendationCitation"
            }
          },
          {
            "type" : "citation",
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                    "code" : "clinical-practice-guideline",
                    "display" : "Clinical practice guideline"
                  }
                ]
              }
            ],
            "resourceReference" : {
              🔗 "reference" : "Citation/ExampleGuidelineCitation"
            }
          }
        ],
        "action" : [
          {
            "title" : "example recommendation",
            "description" : "Example recommendation",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process",
                  "code" : "guideline-based-care"
                }
              ]
            },
            "definitionCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan"
          },
          {
            "title" : "example recommendation",
            "description" : "Example recommendation",
            "code" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/uv/cpg/CodeSystem/cpg-common-process",
                  "code" : "guideline-based-care"
                }
              ]
            },
            "definitionCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan"
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-plan",
      "resource" : {
        "resourceType" : "PlanDefinition",
        "id" : "ExampleRecommendationPlan",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-plan"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"PlanDefinition_ExampleRecommendationPlan\"> </a><p><b>Generated Narrative: PlanDefinition</b><a name=\"ExampleRecommendationPlan\"> </a><a name=\"hcExampleRecommendationPlan\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourcePlanDefinition &quot;ExampleRecommendationPlan&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-plan.html\">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href=\"PlanDefinition-ExampleRecommendation.html\">Recommendation</a></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: Exactly <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-action-combination-method.html\">Action Combination Method</a>#exactly)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 1</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: RecommendationPlan</p><p><b>title</b>: Recommendation Plan</p><p><b>type</b>: ECA Rule <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html\">PlanDefinitionType</a>#eca-rule)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href=\"EvidenceVariable-ExampleRecommendationEligibilityCriteria.html\">PopulationExample</a></p><p><b>date</b>: 2022-02-14</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Example Recommendation Plan</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>ventilator-management-goal</blockquote><p><b>category</b>: Ventilator care and adjustment (regime/therapy) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#385857005)</span></p><p><b>description</b>: The ventilator should be set up to provide a breath reate of at least 20 and at most per minute. <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Breath rate mechanical --on ventilator <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#33438-3)</span></td><td>20-24</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>lab-ddimer-concentration-goal</blockquote><p><b>category</b>: Lab findings surveillance (regime/therapy) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#410394004)</span></p><p><b>description</b>: D-Dimer concentration shall be below 250 ng/mL <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> ()</span></p><h3>Targets</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Fibrin D-dimer DDU [Mass/volume] in Platelet poor plasma <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#48066-5)</span></td><td>?-250</td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Administration of substance (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#432102000)</span></p><p><b>definition</b>: <a href=\"Bundle-GuidelineRecommendationExample.html\">DrugAdministrationAction</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Positioning patient (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#229824005)</span></p><p><b>goalId</b>: ventilator-management-goal</p><p><b>definition</b>: <a href=\"ActivityDefinition-ExampleBodyPositioningAction.html\">DrugAdministrationAction</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Ventilator care management (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#410210009)</span></p><p><b>goalId</b>: ventilator-management-goal</p></blockquote><blockquote><p><b>action</b></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: One or More <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-cs-action-combination-method.html\">Action Combination Method</a>#one-or-more)</span></p></blockquote><p><b>code</b>: Combined (qualifier value) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#89780004)</span></p><h3>Actions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Code</b></td><td><b>GoalId</b></td></tr><tr><td style=\"display: none\">*</td><td>Ventilator care management (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#410210009)</span></td><td>ventilator-management-goal</td></tr></table></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
            "valueCode" : "computable"
          },
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
            "valueCode" : "structured"
          },
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-partOf",
            "valueCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation"
          },
          {
            "extension" : [
              {
                "url" : "method",
                "valueCodeableConcept" : {
                  "coding" : [
                    {
                      "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method",
                      "code" : "exactly"
                    }
                  ]
                }
              },
              {
                "url" : "threshold",
                "valuePositiveInt" : 1
              }
            ],
            "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"
          }
        ],
        "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan",
        "version" : "1.0",
        "name" : "RecommendationPlan",
        "title" : "Recommendation Plan",
        "type" : {
          "coding" : [
            {
              "system" : "http://terminology.hl7.org/CodeSystem/plan-definition-type",
              "code" : "eca-rule"
            }
          ]
        },
        "status" : "active",
        "experimental" : true,
        "subjectCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria",
        "date" : "2022-02-14",
        "publisher" : "CPGonEBMonFHIR",
        "description" : "Example Recommendation Plan",
        "goal" : [
          {
            "id" : "ventilator-management-goal",
            "category" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "385857005",
                  "display" : "Ventilator care and adjustment (regime/therapy)"
                }
              ]
            },
            "description" : {
              "text" : "The ventilator should be set up to provide a breath reate of at least 20 and at most per minute."
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://loinc.org",
                      "code" : "33438-3",
                      "display" : "Breath rate mechanical --on ventilator"
                    }
                  ]
                },
                "detailRange" : {
                  "low" : {
                    "value" : 20,
                    "system" : "http://unitsofmeasure.org",
                    "code" : "/min"
                  },
                  "high" : {
                    "value" : 24,
                    "system" : "http://unitsofmeasure.org",
                    "code" : "/min"
                  }
                }
              }
            ]
          },
          {
            "id" : "lab-ddimer-concentration-goal",
            "category" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "410394004",
                  "display" : "Lab findings surveillance (regime/therapy)"
                }
              ]
            },
            "description" : {
              "text" : "D-Dimer concentration shall be below 250 ng/mL"
            },
            "target" : [
              {
                "measure" : {
                  "coding" : [
                    {
                      "system" : "http://loinc.org",
                      "code" : "48066-5",
                      "display" : "Fibrin D-dimer DDU [Mass/volume] in Platelet poor plasma"
                    }
                  ]
                },
                "detailRange" : {
                  "high" : {
                    "value" : 250,
                    "system" : "http://unitsofmeasure.org",
                    "code" : "ng/mL"
                  }
                }
              }
            ]
          }
        ],
        "action" : [
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "432102000",
                  "display" : "Administration of substance (procedure)"
                }
              ]
            },
            "definitionCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "229824005",
                  "display" : "Positioning patient (procedure)"
                }
              ]
            },
            "goalId" : [
              "ventilator-management-goal"
            ],
            "definitionCanonical" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/body-positioning-example"
          },
          {
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "410210009",
                  "display" : "Ventilator care management (procedure)"
                }
              ]
            },
            "goalId" : [
              "ventilator-management-goal"
            ]
          },
          {
            "extension" : [
              {
                "extension" : [
                  {
                    "url" : "method",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method",
                          "code" : "one-or-more"
                        }
                      ]
                    }
                  }
                ],
                "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method"
              }
            ],
            "code" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "89780004",
                  "display" : "Combined (qualifier value)"
                }
              ]
            },
            "action" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "http://snomed.info/sct",
                      "code" : "410210009",
                      "display" : "Ventilator care management (procedure)"
                    }
                  ]
                },
                "goalId" : [
                  "ventilator-management-goal"
                ]
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-action",
      "resource" : {
        "resourceType" : "ActivityDefinition",
        "id" : "ExampleDrugAdministrationAction",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"
          ]
        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ActivityDefinition_ExampleDrugAdministrationAction\"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name=\"ExampleDrugAdministrationAction\"> </a><a name=\"hcExampleDrugAdministrationAction\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceActivityDefinition &quot;ExampleDrugAdministrationAction&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-drug-administration-action.html\">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: DrugAdministrationAction</p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: Patient <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-fhir-types.html\">All FHIR Types</a>#Patient)</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: A drug administration that should be performed.</p><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: Administration of substance (procedure) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#432102000)</span></p><p><b>product</b>: Dexamethasone (substance) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#372584003; atc#C05AA09 &quot;Dexamethason&quot;)</span></p><blockquote><p><b>dosage</b></p><blockquote><p><b>Dosage Condition</b></p><blockquote><p><b>url</b></p><code>type</code></blockquote><p><b>value</b>: Body weight <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://loinc.org/\">LOINC</a>#29463-7)</span></p><blockquote><p><b>url</b></p><code>value</code></blockquote><p><b>value</b>: ?-70</p></blockquote><p><b>timing</b>: Count 10  times, Duration 10days , Once per 1 days</p><p><b>route</b>: Oral route <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability",
            "valueCode" : "computable"
          },
          {
            "url" : "http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel",
            "valueCode" : "structured"
          }
        ],
        "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example",
        "version" : "1.0",
        "name" : "DrugAdministrationAction",
        "status" : "active",
        "experimental" : true,
        "subjectCodeableConcept" : {
          "coding" : [
            {
              "system" : "http://hl7.org/fhir/fhir-types",
              "code" : "Patient"
            }
          ]
        },
        "publisher" : "CPGonEBMonFHIR",
        "description" : "A drug administration that should be performed.",
        "kind" : "MedicationRequest",
        "code" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "432102000",
              "display" : "Administration of substance (procedure)"
            }
          ]
        },
        "productCodeableConcept" : {
          "coding" : [
            {
              "system" : "http://snomed.info/sct",
              "code" : "372584003",
              "display" : "Dexamethasone (substance)"
            },
            {
              "system" : "http://fhir.de/CodeSystem/bfarm/atc",
              "code" : "C05AA09",
              "display" : "Dexamethason"
            }
          ]
        },
        "dosage" : [
          {
            "extension" : [
              {
                "extension" : [
                  {
                    "url" : "type",
                    "valueCodeableConcept" : {
                      "coding" : [
                        {
                          "system" : "http://loinc.org",
                          "code" : "29463-7",
                          "display" : "Body weight"
                        }
                      ]
                    }
                  },
                  {
                    "url" : "value",
                    "valueRange" : {
                      "high" : {
                        "value" : 70,
                        "unit" : "kg",
                        "system" : "http://unitsofmeasure.org",
                        "code" : "kg"
                      }
                    }
                  }
                ],
                "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-dosage-condition"
              }
            ],
            "timing" : {
              "repeat" : {
                "count" : 10,
                "duration" : 10,
                "durationUnit" : "d",
                "frequency" : 1,
                "period" : 1,
                "periodUnit" : "d"
              }
            },
            "route" : {
              "coding" : [
                {
                  "system" : "http://snomed.info/sct",
                  "code" : "26643006",
                  "display" : "Oral route"
                }
              ]
            },
            "doseAndRate" : [
              {
                "doseQuantity" : {
                  "value" : 6,
                  "unit" : "mg",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "mg"
                },
                "rateQuantity" : {
                  "value" : 1,
                  "unit" : "/d",
                  "system" : "http://unitsofmeasure.org",
                  "code" : "/d"
                }
              }
            ]
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/population",
      "resource" : {
        "resourceType" : "EvidenceVariable",
        "id" : "ExampleRecommendationEligibilityCriteria",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_ExampleRecommendationEligibilityCriteria\"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name=\"ExampleRecommendationEligibilityCriteria\"> </a><a name=\"hcExampleRecommendationEligibilityCriteria\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidenceVariable &quot;ExampleRecommendationEligibilityCriteria&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-eligibility-criteria.html\">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria</code></p><p><b>name</b>: PopulationExample</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Clinical finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote></div>"
        },
        "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria",
        "name" : "PopulationExample",
        "status" : "active",
        "characteristic" : [
          {
            "definitionByTypeAndValue" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "404684003",
                    "display" : "Clinical finding (finding)"
                  }
                ]
              },
              "valueCodeableConcept" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "840539006",
                    "display" : "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"
                  }
                ]
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-justification",
      "resource" : {
        "resourceType" : "ArtifactAssessment",
        "id" : "ExampleRecommendationJustification",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-justification"
          ]
        },
        "text" : {
          "status" : "extensions",
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        },
        "extension" : [
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            "valueString" : "0.1.0"
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          {
            "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status",
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        "date" : "2020-01-03",
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                        "display" : "Certainty of evidence rating"
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                ],
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            "relatedArtifact" : [
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                        "display" : "Net effect"
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                    ]
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                ],
                "resourceReference" : {
                  🔗 "reference" : "Evidence/ExampleNetEffectEstimate"
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    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/certainty-of-evidence-rating",
      "resource" : {
        "resourceType" : "ArtifactAssessment",
        "id" : "ExampleCertaintyOfEvidenceRating",
        "meta" : {
          "profile" : [
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        },
        "text" : {
          "status" : "extensions",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"ArtifactAssessment_ExampleCertaintyOfEvidenceRating\"> </a><p><b>Generated Narrative: ArtifactAssessment</b><a name=\"ExampleCertaintyOfEvidenceRating\"> </a><a name=\"hcExampleCertaintyOfEvidenceRating\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceArtifactAssessment &quot;ExampleCertaintyOfEvidenceRating&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-certainty-of-evidence-rating.html\">Certainty of Evidence Rating</a></p></div><p><b>ArtifactAssessment Version</b>: 0.1.1</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2022-03-11</p><p><b>artifact</b>: See on this page: Evidence/ExampleStudyOutcomeEvidence</p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Overall certainty <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-certainty-type.html\">Evidence Certainty Type</a>#Overall)</span></p><p><b>classifier</b>: Moderate quality <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-certainty-rating.html\">Evidence Certainty Rating</a>#moderate)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Risk of bias <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-certainty-type.html\">Evidence Certainty Type</a>#RiskOfBias)</span></p><p><b>classifier</b>: serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-certainty-rating.html\">Evidence Certainty Rating</a>#serious-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Imprecision <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-certainty-type.html\">Evidence Certainty Type</a>#Imprecision)</span></p><p><b>classifier</b>: serious concern <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-certainty-rating.html\">Evidence Certainty Rating</a>#serious-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Large effect <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-certainty-type.html\">Evidence Certainty Type</a>#LargeEffect)</span></p><p><b>classifier</b>: increase rating: +2 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-certainty-rating.html\">Evidence Certainty Rating</a>#upcode2)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Plausible confounding <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-certainty-type.html\">Evidence Certainty Type</a>#PlausibleConfounding)</span></p><p><b>classifier</b>: increase rating: +1 <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-certainty-rating.html\">Evidence Certainty Rating</a>#upcode1)</span></p></blockquote></div>"
        },
        "extension" : [
          {
            "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version",
            "valueString" : "0.1.1"
          },
          {
            "url" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status",
            "valueCode" : "active"
          }
        ],
        "date" : "2022-03-11",
        "artifactReference" : {
          🔗 "reference" : "Evidence/ExampleStudyOutcomeEvidence"
        },
        "content" : [
          {
            "informationType" : "rating",
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/certainty-type",
                  "code" : "Overall",
                  "display" : "Overall certainty"
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              ]
            },
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/certainty-rating",
                    "code" : "moderate",
                    "display" : "Moderate quality"
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                ]
              }
            ]
          },
          {
            "informationType" : "rating",
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                {
                  "system" : "http://hl7.org/fhir/certainty-type",
                  "code" : "RiskOfBias",
                  "display" : "Risk of bias"
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              ]
            },
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/certainty-rating",
                    "code" : "serious-concern",
                    "display" : "serious concern"
                  }
                ]
              }
            ]
          },
          {
            "informationType" : "rating",
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/certainty-type",
                  "code" : "Imprecision",
                  "display" : "Imprecision"
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              ]
            },
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/certainty-rating",
                    "code" : "serious-concern",
                    "display" : "serious concern"
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              }
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          {
            "informationType" : "rating",
            "type" : {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/certainty-type",
                  "code" : "LargeEffect",
                  "display" : "Large effect"
                }
              ]
            },
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/certainty-rating",
                    "code" : "upcode2",
                    "display" : "increase rating: +2"
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          {
            "informationType" : "rating",
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              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/certainty-type",
                  "code" : "PlausibleConfounding",
                  "display" : "Plausible confounding"
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              ]
            },
            "classifier" : [
              {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/certainty-rating",
                    "code" : "upcode1",
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                ]
              }
            ]
          }
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      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-outcome-evidence",
      "resource" : {
        "resourceType" : "Evidence",
        "id" : "ExampleStudyOutcomeEvidence",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-outcome-evidence"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Evidence_ExampleStudyOutcomeEvidence\"> </a><p><b>Generated Narrative: Evidence</b><a name=\"ExampleStudyOutcomeEvidence\"> </a><a name=\"hcExampleStudyOutcomeEvidence\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidence &quot;ExampleStudyOutcomeEvidence&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-study-outcome-evidence.html\">Study Outcome Evidence</a></p></div><p><b>name</b>: ExampleStudyOutcomeEvidence</p><p><b>status</b>: active</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>citation</td><td>See on this page: Citation/ExampleStudyCitation</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href=\"Group-ExampleStudyCohort.html\">Group/ExampleStudyCohort</a></p><p><b>intended</b>: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: See on this page: EvidenceVariable/ExampleOutcome</p></blockquote><p><b>synthesisType</b>: not applicable <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-synthesis-type.html\">SynthesisType</a>#NotApplicable)</span></p></div>"
        },
        "name" : "ExampleStudyOutcomeEvidence",
        "status" : "active",
        "relatedArtifact" : [
          {
            "type" : "citation",
            "resourceReference" : {
              🔗 "reference" : "Citation/ExampleStudyCitation"
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          }
        ],
        "variableDefinition" : [
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            "variableRole" : {
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                {
                  "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
                  "code" : "population"
                }
              ]
            },
            "observed" : {
              🔗 "reference" : "Group/ExampleStudyCohort"
            },
            "intended" : {
              🔗 "reference" : "EvidenceVariable/ExampleStudyEligibilityCriteria"
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          {
            "variableRole" : {
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              🔗 "reference" : "EvidenceVariable/ExampleOutcome"
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        ],
        "synthesisType" : {
          "coding" : [
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              "system" : "http://terminology.hl7.org/CodeSystem/synthesis-type",
              "code" : "NotApplicable"
            }
          ]
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      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome-evidence-synthesis",
      "resource" : {
        "resourceType" : "Evidence",
        "id" : "ExampleOutcomeEvidenceSynthesis",
        "meta" : {
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          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Evidence_ExampleOutcomeEvidenceSynthesis\"> </a><p><b>Generated Narrative: Evidence</b><a name=\"ExampleOutcomeEvidenceSynthesis\"> </a><a name=\"hcExampleOutcomeEvidenceSynthesis\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidence &quot;ExampleOutcomeEvidenceSynthesis&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-outcome-evidence-synthesis.html\">Outcome Evidence Synthesis</a></p></div><p><b>name</b>: ExampleOutcomeEvidenceSynthesis</p><p><b>status</b>: active</p><h3>RelatedArtifacts</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style=\"display: none\">*</td><td>citation</td><td>See on this page: Citation/ExampleStudyCitation</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href=\"Group-ExampleEvidenceSynthesisCohorts.html\">Group/ExampleEvidenceSynthesisCohorts</a></p><p><b>intended</b>: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: See on this page: EvidenceVariable/ExampleOutcome</p></blockquote><p><b>synthesisType</b>: not applicable <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-synthesis-type.html\">SynthesisType</a>#NotApplicable)</span></p></div>"
        },
        "name" : "ExampleOutcomeEvidenceSynthesis",
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        "relatedArtifact" : [
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            "resourceReference" : {
              🔗 "reference" : "Citation/ExampleStudyCitation"
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                {
                  "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
                  "code" : "population"
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              ]
            },
            "observed" : {
              🔗 "reference" : "Group/ExampleEvidenceSynthesisCohorts"
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            "intended" : {
              🔗 "reference" : "EvidenceVariable/ExampleStudyEligibilityCriteria"
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          },
          {
            "variableRole" : {
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              🔗 "reference" : "EvidenceVariable/ExampleOutcome"
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        "synthesisType" : {
          "coding" : [
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    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-eligbility-criteria",
      "resource" : {
        "resourceType" : "EvidenceVariable",
        "id" : "ExampleStudyEligibilityCriteria",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-eligibility-criteria"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_ExampleStudyEligibilityCriteria\"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name=\"ExampleStudyEligibilityCriteria\"> </a><a name=\"hcExampleStudyEligibilityCriteria\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidenceVariable &quot;ExampleStudyEligibilityCriteria&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-study-eligibility-criteria.html\">Study Eligibility Criteria</a></p></div><p><b>name</b>: ExampleStudyEligibilityCriteria</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Clinical finding (finding) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote></div>"
        },
        "name" : "ExampleStudyEligibilityCriteria",
        "status" : "active",
        "characteristic" : [
          {
            "definitionByTypeAndValue" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "404684003",
                    "display" : "Clinical finding (finding)"
                  }
                ]
              },
              "valueCodeableConcept" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "840539006",
                    "display" : "Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"
                  }
                ]
              }
            }
          }
        ]
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-citation",
      "resource" : {
        "resourceType" : "Citation",
        "id" : "ExampleStudyCitation",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-citation"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_ExampleStudyCitation\"> </a><p><b>Generated Narrative: Citation</b><a name=\"ExampleStudyCitation\"> </a><a name=\"hcExampleStudyCitation\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceCitation &quot;ExampleStudyCitation&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-study-citation.html\">Study Citation</a></p></div><p><b>name</b>: ExampleCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td>Example Citation</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>Publication Type <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Journal Article <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-citation-artifact-classifier.html\">Citation Artifact Classifier</a>#D016428)</span></td></tr></table></blockquote></div>"
        },
        "name" : "ExampleCitation",
        "status" : "active",
        "citedArtifact" : {
          "identifier" : [
            {
              "value" : "ceoysy/exampleIdentifier"
            }
          ],
          "title" : [
            {
              "text" : "Example Citation"
            }
          ],
          "classification" : [
            {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/cited-artifact-classification-type",
                    "code" : "publication-type",
                    "display" : "Publication Type"
                  }
                ]
              },
              "classifier" : [
                {
                  "coding" : [
                    {
                      "system" : "http://hl7.org/fhir/citation-artifact-classifier",
                      "code" : "D016428",
                      "display" : "Journal Article"
                    }
                  ]
                }
              ]
            }
          ]
        }
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome",
      "resource" : {
        "resourceType" : "EvidenceVariable",
        "id" : "ExampleOutcome",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-definition"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"EvidenceVariable_ExampleOutcome\"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name=\"ExampleOutcome\"> </a><a name=\"hcExampleOutcome\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidenceVariable &quot;ExampleOutcome&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-outcome-definition.html\">Outcome Definition</a></p></div><p><b>identifier</b>: <code>https://www.ceosys.de</code>/outcome-example</p><p><b>name</b>: Mortality</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style=\"display: none\">*</td><td>Mortality rate (observable entity) <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"https://browser.ihtsdotools.org/\">SNOWMED CT</a>#409651001)</span></td><td> percent<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></td></tr></table></blockquote><p><b>handling</b>: dichotomous</p></div>"
        },
        "identifier" : [
          {
            "system" : "https://www.ceosys.de",
            "value" : "outcome-example"
          }
        ],
        "name" : "Mortality",
        "status" : "active",
        "characteristic" : [
          {
            "exclude" : false,
            "definitionByTypeAndValue" : {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://snomed.info/sct",
                    "code" : "409651001",
                    "display" : "Mortality rate (observable entity)"
                  }
                ]
              },
              "valueQuantity" : {
                "unit" : "percent",
                "system" : "http://unitsofmeasure.org",
                "code" : "%"
              }
            }
          }
        ],
        "handling" : "dichotomous"
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-citation",
      "resource" : {
        "resourceType" : "Citation",
        "id" : "ExampleRecommendationCitation",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Citation_ExampleRecommendationCitation\"> </a><p><b>Generated Narrative: Citation</b><a name=\"ExampleRecommendationCitation\"> </a><a name=\"hcExampleRecommendationCitation\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceCitation &quot;ExampleRecommendationCitation&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-recommendation-citation.html\">Recommendation Citation</a></p></div><p><b>name</b>: ExampleRecommendationCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Versions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Value</b></td></tr><tr><td style=\"display: none\">*</td><td>1.0-alpha1</td></tr></table><p><b>currentState</b>: Archived <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html\">Cited Artifact Status Type</a>#archived)</span></p><h3>Titles</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Text</b></td></tr><tr><td style=\"display: none\">*</td><td>Example Citation</td></tr></table><h3>Classifications</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style=\"display: none\">*</td><td>Publication Type <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html\">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline recommendation <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#guideline-recommendation)</span></td></tr></table></blockquote></div>"
        },
        "name" : "ExampleRecommendationCitation",
        "status" : "active",
        "citedArtifact" : {
          "identifier" : [
            {
              "value" : "ceoysy/exampleIdentifier"
            }
          ],
          "version" : {
            "value" : "1.0-alpha1"
          },
          "currentState" : [
            {
              "coding" : [
                {
                  "system" : "http://hl7.org/fhir/cited-artifact-status-type",
                  "code" : "archived",
                  "display" : "Archived"
                }
              ]
            }
          ],
          "title" : [
            {
              "text" : "Example Citation"
            }
          ],
          "classification" : [
            {
              "type" : {
                "coding" : [
                  {
                    "system" : "http://hl7.org/fhir/cited-artifact-classification-type",
                    "code" : "publication-type",
                    "display" : "Publication Type"
                  }
                ]
              },
              "classifier" : [
                {
                  "coding" : [
                    {
                      "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                      "code" : "guideline-recommendation",
                      "display" : "Clinical practice guideline recommendation"
                    }
                  ]
                }
              ]
            }
          ]
        }
      }
    },
    {
      "fullUrl" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/net-effect-estimate",
      "resource" : {
        "resourceType" : "Evidence",
        "id" : "ExampleNetEffectEstimate",
        "meta" : {
          "profile" : [
            🔗 "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/net-effect-estimate"
          ]
        },
        "text" : {
          "status" : "generated",
          "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><a name=\"Evidence_ExampleNetEffectEstimate\"> </a><p><b>Generated Narrative: Evidence</b><a name=\"ExampleNetEffectEstimate\"> </a><a name=\"hcExampleNetEffectEstimate\"> </a></p><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\">ResourceEvidence &quot;ExampleNetEffectEstimate&quot; </p><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-net-effect-estimate.html\">Net Effect Estimate</a></p></div><p><b>name</b>: NetEffectExample</p><p><b>status</b>: unknown</p><h3>VariableDefinitions</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>VariableRole</b></td><td><b>Intended</b></td></tr><tr><td style=\"display: none\">*</td><td>measured variable <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html\">EvidenceVariableRole</a>#measuredVariable)</span></td><td>See on this page: EvidenceVariable/ExampleOutcome</td></tr></table><blockquote><p><b>statistic</b></p><p><b>description</b>: Net Effect</p><p><b>statisticType</b>: Net Effect <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#net-effect)</span></p><p><b>quantity</b>: 1.7 %<span style=\"background: LightGoldenRodYellow\"> (Details: UCUM code % = '%')</span></p><h3>AttributeEstimates</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style=\"display: none\">*</td><td>Confidence interval <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"http://terminology.hl7.org/5.5.0/CodeSystem-attribute-estimate-type.html\">StatisticAttribute Estimate Type</a>#C53324)</span></td><td>0.95</td><td>1.5-1.9</td></tr></table><blockquote><p><b>modelCharacteristic</b></p><p><b>code</b>: Relative importance weighting for use in weighted linear combinations <span style=\"background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki\"> (<a href=\"CodeSystem-ceosys-code-system.html\">CEOsys Code System</a>#relative-importance-weighting)</span></p><p><b>value</b>: 1</p><h3>Variables</h3><table class=\"grid\"><tr><td style=\"display: none\">-</td><td><b>VariableDefinition</b></td></tr><tr><td style=\"display: none\">*</td><td>See on this page: EvidenceVariable/ExampleOutcome</td></tr></table></blockquote></blockquote></div>"
        },
        "name" : "NetEffectExample",
        "status" : "unknown",
        "variableDefinition" : [
          {
            "variableRole" : {
              "coding" : [
                {
                  "system" : "http://terminology.hl7.org/CodeSystem/variable-role",
                  "code" : "measuredVariable"
                }
              ]
            },
            "intended" : {
              🔗 "reference" : "EvidenceVariable/ExampleOutcome"
            }
          }
        ],
        "statistic" : [
          {
            "description" : "Net Effect",
            "statisticType" : {
              "coding" : [
                {
                  "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                  "code" : "net-effect",
                  "display" : "Net Effect"
                }
              ]
            },
            "quantity" : {
              "value" : 1.7,
              "system" : "http://unitsofmeasure.org",
              "code" : "%"
            },
            "attributeEstimate" : [
              {
                "type" : {
                  "coding" : [
                    {
                      "system" : "http://terminology.hl7.org/CodeSystem/attribute-estimate-type",
                      "code" : "C53324",
                      "display" : "Confidence interval"
                    }
                  ]
                },
                "level" : 0.95,
                "range" : {
                  "low" : {
                    "value" : 1.5,
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  },
                  "high" : {
                    "value" : 1.9,
                    "system" : "http://unitsofmeasure.org",
                    "code" : "%"
                  }
                }
              }
            ],
            "modelCharacteristic" : [
              {
                "code" : {
                  "coding" : [
                    {
                      "system" : "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system",
                      "code" : "relative-importance-weighting"
                    }
                  ]
                },
                "value" : {
                  "value" : 1
                },
                "variable" : [
                  {
                    "variableDefinition" : {
                      🔗 "reference" : "EvidenceVariable/ExampleOutcome"
                    }
                  }
                ]
              }
            ]
          }
        ]
      }
    }
  ]
}