Bundle GuidelineRecommendationExample of type collection

Entry 1 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example

Resource Composition:

Generated Narrative: Composition

ResourceComposition "GuidelineExample"

Profile: Clinical Practice Guideline

identifier: Resource identifier/guideline example

version: 0.1.0

status: FINAL

type: Guidelines (CEOsys Code System#clinical-practice-guideline; #e07eN1w1Rwswg4)

category: Evidence- and consensus-based guideline (Guideline Stage Classification#S3)

date: 2022-01-28

author: Organization/ExampleOrganization "Example Organization"

title: Example Guideline

RelatesTos

-	Type	ResourceReference
*	CITATION	See on this page: Citation/ExampleGuidelineCitation

Entry 2 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/citation

Resource Citation:

Generated Narrative: Citation

ResourceCitation "ExampleGuidelineCitation"

Profile: Guideline Citation

name: ExampleGuidelineCitation

status: ACTIVE

citedArtifact

identifier: ceoysy/exampleIdentifier

Versions

-	Value
*	1.0-alpha1

currentState: Archived (Cited Artifact Status Type#archived)

Titles

-	Text
*	Example Citation

WebLocations

-	Url
*	https://example.com/guideline/exampleIdentifier

Classifications

-	Type	Classifier
*	Publication Type (Cited Artifact Classification Type#publication-type)	Clinical practice guideline (CEOsys Code System#clinical-practice-guideline)

Entry 3 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation

Resource PlanDefinition:

Generated Narrative: PlanDefinition

ResourcePlanDefinition "ExampleRecommendation"

Profile: Recommendation

knowledgeCapability: computable

knowledgeRepresentationLevel: structured

Action Combination Method

url

method

value: At Least (Action Combination Method#at-least)

url

threshold

value: 2

url: https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation

version: 1.0

name: Recommendation

title: Recommendation

type: Workflow Definition (PlanDefinitionType#workflow-definition)

status: ACTIVE

experimental: true

date: 2022-02-14

publisher: CPGonEBMonFHIR

description: Example Recommendation

RelatedArtifacts

-	Type	Classifier	ResourceReference
*	JUSTIFICATION	Recommendation rating (CEOsys Code System#recommendation-rating)	See on this page: ArtifactAssessment/ExampleRecommendationJustification
*	CITATION	Clinical practice guideline recommendation (CEOsys Code System#guideline-recommendation)	See on this page: Citation/ExampleRecommendationCitation
*	CITATION	Clinical practice guideline (CEOsys Code System#clinical-practice-guideline)	See on this page: Citation/ExampleGuidelineCitation

action

title: example recommendation

description: Example recommendation

code: Guideline-based Care (CPG Common Process#guideline-based-care)

definition: Recommendation Plan

action

title: example recommendation

description: Example recommendation

code: Guideline-based Care (CPG Common Process#guideline-based-care)

definition: Recommendation Plan

Entry 4 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-plan

Resource PlanDefinition:

Generated Narrative: PlanDefinition

ResourcePlanDefinition "ExampleRecommendationPlan"

Profile: Recommendation Plan

knowledgeCapability: computable

knowledgeRepresentationLevel: structured

partOf: Recommendation

Action Combination Method

url

method

value: Exactly (Action Combination Method#exactly)

url

threshold

value: 1

url: https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan

version: 1.0

name: RecommendationPlan

title: Recommendation Plan

type: ECA Rule (PlanDefinitionType#eca-rule)

status: ACTIVE

experimental: true

subject: PopulationExample

date: 2022-02-14

publisher: CPGonEBMonFHIR

description: Example Recommendation Plan

goal

id

ventilator-management-goal

category: Ventilator care and adjustment (regime/therapy) (SNOWMED CT#385857005)

description: The ventilator should be set up to provide a breath reate of at least 20 and at most per minute. ()

Targets

-	Measure	Detail[x]
*	Breath rate mechanical --on ventilator (LOINC#33438-3)	20-24

goal

id

lab-ddimer-concentration-goal

category: Lab findings surveillance (regime/therapy) (SNOWMED CT#410394004)

description: D-Dimer concentration shall be below 250 ng/mL ()

Targets

-	Measure	Detail[x]
*	Fibrin D-dimer DDU [Mass/volume] in Platelet poor plasma (LOINC#48066-5)	?-250

action

code: Administration of substance (procedure) (SNOWMED CT#432102000)

definition: DrugAdministrationAction

action

code: Positioning patient (procedure) (SNOWMED CT#229824005)

goalId: ventilator-management-goal

definition: DrugAdministrationAction

action

code: Ventilator care management (procedure) (SNOWMED CT#410210009)

goalId: ventilator-management-goal

action

Action Combination Method

url

method

value: One or More (Action Combination Method#one-or-more)

code: Combined (qualifier value) (SNOWMED CT#89780004)

Actions

-	Code	GoalId
*	Ventilator care management (procedure) (SNOWMED CT#410210009)	ventilator-management-goal

Entry 5 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-action

Resource ActivityDefinition:

Generated Narrative: ActivityDefinition

ResourceActivityDefinition "ExampleDrugAdministrationAction"

Profile: Drug Administration Action

knowledgeCapability: computable

knowledgeRepresentationLevel: structured

url: https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example

version: 1.0

name: DrugAdministrationAction

status: ACTIVE

experimental: true

subject: Patient (All FHIR Types#Patient)

publisher: CPGonEBMonFHIR

description: A drug administration that should be performed.

kind: MEDICATIONREQUEST

code: Administration of substance (procedure) (SNOWMED CT#432102000)

product: Dexamethasone (substance) (SNOWMED CT#372584003; atc#C05AA09 "Dexamethason")

dosage

Dosage Condition

url

type

value: Body weight (LOINC#29463-7)

url

value

value: ?-70

Entry 6 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/population

Resource EvidenceVariable:

Generated Narrative: EvidenceVariable

ResourceEvidenceVariable "ExampleRecommendationEligibilityCriteria"

Profile: Recommendation Eligibility Criteria

url: https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria

name: PopulationExample

status: ACTIVE

characteristic

DefinitionByTypeAndValues

-	Type	Value[x]
*	Clinical finding (finding) (SNOWMED CT#404684003)	Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) (SNOWMED CT#840539006)

Entry 7 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-justification

Resource ArtifactAssessment:

Generated Narrative: ArtifactAssessment

ResourceArtifactAssessment "ExampleRecommendationJustification"

Profile: Recommendation Justification

ArtifactAssessment Version: 0.1.0

ArtifactAssessment Publication Status: active

date: 2020-01-03

artifact: See on this page: PlanDefinition/ExampleRecommendationPlan

content

informationType: RATING

type: Strength of recommendation (CEOsys Code System#strength)

classifier: Strong for an intervention (Recommendation Strength#strong-for)

content

informationType: RATING

type: Overall certainty (Evidence Certainty Type#Overall)

classifier: Very low quality (Evidence Certainty Rating#very-low)

content

informationType: RATING

type: Consensus (CEOsys Code System#consensus)

classifier: Strong (StrengthOfRecommendationRating#strong)

content

informationType: CONTAINER

type: Certainty of evidence rating (CEOsys Code System#certainty-of-evidence-rating)

RelatedArtifacts

-	Type	Classifier	ResourceReference
*	JUSTIFICATION	Certainty of evidence rating (CEOsys Code System#certainty-of-evidence-rating)	See on this page: ArtifactAssessment/ExampleCertaintyOfEvidenceRating

content

informationType: CONTAINER

type: Net effect (CEOsys Code System#net-effect)

RelatedArtifacts

-	Type	Classifier	ResourceReference
*	SUPPORTEDWITH	Net effect (CEOsys Code System#net-effect)	See on this page: Evidence/ExampleNetEffectEstimate

Entry 8 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/certainty-of-evidence-rating

Resource ArtifactAssessment:

Generated Narrative: ArtifactAssessment

ResourceArtifactAssessment "ExampleCertaintyOfEvidenceRating"

Profile: Certainty of Evidence Rating

ArtifactAssessment Version: 0.1.1

ArtifactAssessment Publication Status: active

date: 2022-03-11

artifact: See on this page: Evidence/ExampleStudyOutcomeEvidence

content

informationType: RATING

type: Overall certainty (Evidence Certainty Type#Overall)

classifier: Moderate quality (Evidence Certainty Rating#moderate)

content

informationType: RATING

type: Risk of bias (Evidence Certainty Type#RiskOfBias)

classifier: serious concern (Evidence Certainty Rating#serious-concern)

content

informationType: RATING

type: Imprecision (Evidence Certainty Type#Imprecision)

classifier: serious concern (Evidence Certainty Rating#serious-concern)

content

informationType: RATING

type: Large effect (Evidence Certainty Type#LargeEffect)

classifier: increase rating: +2 (Evidence Certainty Rating#upcode2)

content

informationType: RATING

type: Plausible confounding (Evidence Certainty Type#PlausibleConfounding)

classifier: increase rating: +1 (Evidence Certainty Rating#upcode1)

Entry 9 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-outcome-evidence

Resource Evidence:

Generated Narrative: Evidence

ResourceEvidence "ExampleStudyOutcomeEvidence"

Profile: Study Outcome Evidence

name: ExampleStudyOutcomeEvidence

status: ACTIVE

RelatedArtifacts

-	Type	ResourceReference
*	CITATION	See on this page: Citation/ExampleStudyCitation

variableDefinition

variableRole: population (EvidenceVariableRole#population)

observed: Group/ExampleStudyCohort

intended: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria

variableDefinition

variableRole: measured variable (EvidenceVariableRole#measuredVariable)

observed: See on this page: EvidenceVariable/ExampleOutcome

synthesisType: not applicable (SynthesisType#NotApplicable)

Entry 10 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome-evidence-synthesis

Resource Evidence:

Generated Narrative: Evidence

ResourceEvidence "ExampleOutcomeEvidenceSynthesis"

Profile: Outcome Evidence Synthesis

name: ExampleOutcomeEvidenceSynthesis

status: ACTIVE

RelatedArtifacts

-	Type	ResourceReference
*	CITATION	See on this page: Citation/ExampleStudyCitation

variableDefinition

variableRole: population (EvidenceVariableRole#population)

observed: Group/ExampleEvidenceSynthesisCohorts

intended: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria

variableDefinition

variableRole: measured variable (EvidenceVariableRole#measuredVariable)

observed: See on this page: EvidenceVariable/ExampleOutcome

synthesisType: not applicable (SynthesisType#NotApplicable)

Entry 11 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-eligbility-criteria

Resource EvidenceVariable:

Generated Narrative: EvidenceVariable

ResourceEvidenceVariable "ExampleStudyEligibilityCriteria"

Profile: Study Eligibility Criteria

name: ExampleStudyEligibilityCriteria

status: ACTIVE

characteristic

DefinitionByTypeAndValues

-	Type	Value[x]
*	Clinical finding (finding) (SNOWMED CT#404684003)	Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) (SNOWMED CT#840539006)

Entry 12 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-citation

Resource Citation:

Generated Narrative: Citation

ResourceCitation "ExampleStudyCitation"

Profile: Study Citation

name: ExampleCitation

status: ACTIVE

citedArtifact

identifier: ceoysy/exampleIdentifier

Titles

-	Text
*	Example Citation

Classifications

-	Type	Classifier
*	Publication Type (Cited Artifact Classification Type#publication-type)	Journal Article (Citation Artifact Classifier#D016428)

Entry 13 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome

Resource EvidenceVariable:

Generated Narrative: EvidenceVariable

ResourceEvidenceVariable "ExampleOutcome"

Profile: Outcome Definition

identifier: https://www.ceosys.de/outcome-example

name: Mortality

status: ACTIVE

characteristic

exclude: false

DefinitionByTypeAndValues

-	Type	Value[x]
*	Mortality rate (observable entity) (SNOWMED CT#409651001)	percent (Details: UCUM code % = '%')

handling: DICHOTOMOUS

Entry 14 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-citation

Resource Citation:

Generated Narrative: Citation

ResourceCitation "ExampleRecommendationCitation"

Profile: Recommendation Citation

name: ExampleRecommendationCitation

status: ACTIVE

citedArtifact

identifier: ceoysy/exampleIdentifier

Versions

-	Value
*	1.0-alpha1

currentState: Archived (Cited Artifact Status Type#archived)

Titles

-	Text
*	Example Citation

Classifications

-	Type	Classifier
*	Publication Type (Cited Artifact Classification Type#publication-type)	Clinical practice guideline recommendation (CEOsys Code System#guideline-recommendation)

Entry 15 - fullUrl = https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/net-effect-estimate

Resource Evidence:

Generated Narrative: Evidence

ResourceEvidence "ExampleNetEffectEstimate"

Profile: Net Effect Estimate

name: NetEffectExample

status: UNKNOWN

VariableDefinitions

-	VariableRole	Intended
*	measured variable (EvidenceVariableRole#measuredVariable)	See on this page: EvidenceVariable/ExampleOutcome

statistic

description: Net Effect

statisticType: Net Effect (CEOsys Code System#net-effect)

quantity: 1.7 % (Details: UCUM code % = '%')

AttributeEstimates

-	Type	Level	Range
*	Confidence interval (StatisticAttribute Estimate Type#C53324)	0.95	1.5-1.9

modelCharacteristic

code: Relative importance weighting for use in weighted linear combinations (CEOsys Code System#relative-importance-weighting)

value: 1

Variables

-	VariableDefinition
*	See on this page: EvidenceVariable/ExampleOutcome