Clinical Practice Guidelines (CPG) on EBMonFHIR
0.8.0-snapshot - ci-build
Clinical Practice Guidelines (CPG) on EBMonFHIR
0.8.0-snapshot - ci-build
Clinical Practice Guidelines (CPG) on EBMonFHIR - Local Development build (v0.8.0-snapshot) built by the FHIR (HL7® FHIR® Standard) Build Tools. See the Directory of published versions
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Composition_GuidelineExample"> </a><p><b>Generated Narrative: Composition</b><a name="GuidelineExample"> </a><a name="hcGuidelineExample"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceComposition "GuidelineExample" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-guideline.html">Clinical Practice Guideline</a></p></div><p><b>identifier</b>: Resource identifier/guideline example</p><p><b>version</b>: 0.1.0</p><p><b>status</b>: final</p><p><b>type</b>: Guidelines <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline; #e07eN1w1Rwswg4)</span></p><p><b>category</b>: Evidence- and consensus-based guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-guideline-stage-classification.html">Guideline Stage Classification</a>#S3)</span></p><p><b>date</b>: 2022-01-28</p><p><b>author</b>: <a href="Organization-ExampleOrganization.html">Organization/ExampleOrganization</a> "Example Organization"</p><p><b>title</b>: Example Guideline</p><h3>RelatesTos</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td>See on this page: Citation/ExampleGuidelineCitation</td></tr></table></div>
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<display value="Clinical practice guideline recommendation"/>
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<div xmlns="http://www.w3.org/1999/xhtml">This is an example guideline recommendation.</div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="Citation_ExampleGuidelineCitation"> </a><p><b>Generated Narrative: Citation</b><a name="ExampleGuidelineCitation"> </a><a name="hcExampleGuidelineCitation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceCitation "ExampleGuidelineCitation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-guideline-citation.html">Guideline Citation</a></p></div><p><b>name</b>: ExampleGuidelineCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Versions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Value</b></td></tr><tr><td style="display: none">*</td><td>1.0-alpha1</td></tr></table><p><b>currentState</b>: Archived <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html">Cited Artifact Status Type</a>#archived)</span></p><h3>Titles</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Text</b></td></tr><tr><td style="display: none">*</td><td>Example Citation</td></tr></table><h3>WebLocations</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Url</b></td></tr><tr><td style="display: none">*</td><td><a href="https://example.com/guideline/exampleIdentifier">https://example.com/guideline/exampleIdentifier</a></td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style="display: none">*</td><td>Publication Type <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline)</span></td></tr></table></blockquote></div>
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<div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_ExampleRecommendation"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="ExampleRecommendation"> </a><a name="hcExampleRecommendation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourcePlanDefinition "ExampleRecommendation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation.html">Recommendation</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: At Least <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#at-least)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 2</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: Recommendation</p><p><b>title</b>: Recommendation</p><p><b>type</b>: Workflow Definition <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#workflow-definition)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>date</b>: 2022-02-14</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Example Recommendation</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>justification</td><td>Recommendation rating <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#recommendation-rating)</span></td><td>See on this page: ArtifactAssessment/ExampleRecommendationJustification</td></tr><tr><td style="display: none">*</td><td>citation</td><td>Clinical practice guideline recommendation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#guideline-recommendation)</span></td><td>See on this page: Citation/ExampleRecommendationCitation</td></tr><tr><td style="display: none">*</td><td>citation</td><td>Clinical practice guideline <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#clinical-practice-guideline)</span></td><td>See on this page: Citation/ExampleGuidelineCitation</td></tr></table><blockquote><p><b>action</b></p><p><b>title</b>: example recommendation</p><p><b>description</b>: Example recommendation</p><p><b>code</b>: Guideline-based Care <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href="PlanDefinition-ExampleRecommendationPlan.html">Recommendation Plan</a></p></blockquote><blockquote><p><b>action</b></p><p><b>title</b>: example recommendation</p><p><b>description</b>: Example recommendation</p><p><b>code</b>: Guideline-based Care <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/uv/cpg/STU1/CodeSystem-cpg-common-process.html">CPG Common Process</a>#guideline-based-care)</span></p><p><b>definition</b>: <a href="PlanDefinition-ExampleRecommendationPlan.html">Recommendation Plan</a></p></blockquote></div>
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<url
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<version value="1.0"/>
<name value="Recommendation"/>
<title value="Recommendation"/>
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<display value="Recommendation rating"/>
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<coding>
<system
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<code value="guideline-recommendation"/>
<display value="Clinical practice guideline recommendation"/>
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<reference value="Citation/ExampleRecommendationCitation"/>
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<code value="clinical-practice-guideline"/>
<display value="Clinical practice guideline"/>
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<resourceReference>🔗
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<description value="Example recommendation"/>
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<title value="example recommendation"/>
<description value="Example recommendation"/>
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<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="PlanDefinition_ExampleRecommendationPlan"> </a><p><b>Generated Narrative: PlanDefinition</b><a name="ExampleRecommendationPlan"> </a><a name="hcExampleRecommendationPlan"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourcePlanDefinition "ExampleRecommendationPlan" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-plan.html">Recommendation Plan</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>partOf</b>: <a href="PlanDefinition-ExampleRecommendation.html">Recommendation</a></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: Exactly <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#exactly)</span></p><blockquote><p><b>url</b></p><code>threshold</code></blockquote><p><b>value</b>: 1</p></blockquote><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: RecommendationPlan</p><p><b>title</b>: Recommendation Plan</p><p><b>type</b>: ECA Rule <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-plan-definition-type.html">PlanDefinitionType</a>#eca-rule)</span></p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: <a href="EvidenceVariable-ExampleRecommendationEligibilityCriteria.html">PopulationExample</a></p><p><b>date</b>: 2022-02-14</p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: Example Recommendation Plan</p><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>ventilator-management-goal</blockquote><p><b>category</b>: Ventilator care and adjustment (regime/therapy) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#385857005)</span></p><p><b>description</b>: The ventilator should be set up to provide a breath reate of at least 20 and at most per minute. <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Breath rate mechanical --on ventilator <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#33438-3)</span></td><td>20-24</td></tr></table></blockquote><blockquote><p><b>goal</b></p><blockquote><p><b>id</b></p>lab-ddimer-concentration-goal</blockquote><p><b>category</b>: Lab findings surveillance (regime/therapy) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#410394004)</span></p><p><b>description</b>: D-Dimer concentration shall be below 250 ng/mL <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> ()</span></p><h3>Targets</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Measure</b></td><td><b>Detail[x]</b></td></tr><tr><td style="display: none">*</td><td>Fibrin D-dimer DDU [Mass/volume] in Platelet poor plasma <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#48066-5)</span></td><td>?-250</td></tr></table></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>definition</b>: <a href="Bundle-GuidelineRecommendationExample.html">DrugAdministrationAction</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Positioning patient (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#229824005)</span></p><p><b>goalId</b>: ventilator-management-goal</p><p><b>definition</b>: <a href="ActivityDefinition-ExampleBodyPositioningAction.html">DrugAdministrationAction</a></p></blockquote><blockquote><p><b>action</b></p><p><b>code</b>: Ventilator care management (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#410210009)</span></p><p><b>goalId</b>: ventilator-management-goal</p></blockquote><blockquote><p><b>action</b></p><blockquote><p><b>Action Combination Method</b></p><blockquote><p><b>url</b></p><code>method</code></blockquote><p><b>value</b>: One or More <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-cs-action-combination-method.html">Action Combination Method</a>#one-or-more)</span></p></blockquote><p><b>code</b>: Combined (qualifier value) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#89780004)</span></p><h3>Actions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Code</b></td><td><b>GoalId</b></td></tr><tr><td style="display: none">*</td><td>Ventilator care management (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#410210009)</span></td><td>ventilator-management-goal</td></tr></table></blockquote></div>
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<extension
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<valueCanonical
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<extension
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<extension url="method">
<valueCodeableConcept>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"/>
<code value="exactly"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="threshold">
<valuePositiveInt value="1"/>
</extension>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-plan/example-recommendation-plan"/>
<version value="1.0"/>
<name value="RecommendationPlan"/>
<title value="Recommendation Plan"/>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/plan-definition-type"/>
<code value="eca-rule"/>
</coding>
</type>
<status value="active"/>
<experimental value="true"/>
<subjectCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria"/>
<date value="2022-02-14"/>
<publisher value="CPGonEBMonFHIR"/>
<description value="Example Recommendation Plan"/>
<goal id="ventilator-management-goal">
<category>
<coding>
<system value="http://snomed.info/sct"/>
<code value="385857005"/>
<display
value="Ventilator care and adjustment (regime/therapy)"/>
</coding>
</category>
<description>
<text
value="The ventilator should be set up to provide a breath reate of at least 20 and at most per minute."/>
</description>
<target>
<measure>
<coding>
<system value="http://loinc.org"/>
<code value="33438-3"/>
<display value="Breath rate mechanical --on ventilator"/>
</coding>
</measure>
<detailRange>
<low>
<value value="20"/>
<system value="http://unitsofmeasure.org"/>
<code value="/min"/>
</low>
<high>
<value value="24"/>
<system value="http://unitsofmeasure.org"/>
<code value="/min"/>
</high>
</detailRange>
</target>
</goal>
<goal id="lab-ddimer-concentration-goal">
<category>
<coding>
<system value="http://snomed.info/sct"/>
<code value="410394004"/>
<display value="Lab findings surveillance (regime/therapy)"/>
</coding>
</category>
<description>
<text value="D-Dimer concentration shall be below 250 ng/mL"/>
</description>
<target>
<measure>
<coding>
<system value="http://loinc.org"/>
<code value="48066-5"/>
<display
value="Fibrin D-dimer DDU [Mass/volume] in Platelet poor plasma"/>
</coding>
</measure>
<detailRange>
<high>
<value value="250"/>
<system value="http://unitsofmeasure.org"/>
<code value="ng/mL"/>
</high>
</detailRange>
</target>
</goal>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<definitionCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example"/>
</action>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="229824005"/>
<display value="Positioning patient (procedure)"/>
</coding>
</code>
<goalId value="ventilator-management-goal"/>
<definitionCanonical
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/body-positioning-example"/>
</action>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="410210009"/>
<display value="Ventilator care management (procedure)"/>
</coding>
</code>
<goalId value="ventilator-management-goal"/>
</action>
<action>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-action-combination-method">
<extension url="method">
<valueCodeableConcept>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/cs-action-combination-method"/>
<code value="one-or-more"/>
</coding>
</valueCodeableConcept>
</extension>
</extension>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="89780004"/>
<display value="Combined (qualifier value)"/>
</coding>
</code>
<action>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="410210009"/>
<display value="Ventilator care management (procedure)"/>
</coding>
</code>
<goalId value="ventilator-management-goal"/>
</action>
</action>
</PlanDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-action"/>
<resource>
<ActivityDefinition>
<id value="ExampleDrugAdministrationAction"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/drug-administration-action"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ActivityDefinition_ExampleDrugAdministrationAction"> </a><p><b>Generated Narrative: ActivityDefinition</b><a name="ExampleDrugAdministrationAction"> </a><a name="hcExampleDrugAdministrationAction"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceActivityDefinition "ExampleDrugAdministrationAction" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-drug-administration-action.html">Drug Administration Action</a></p></div><p><b>knowledgeCapability</b>: computable</p><p><b>knowledgeRepresentationLevel</b>: structured</p><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example</code></p><p><b>version</b>: 1.0</p><p><b>name</b>: DrugAdministrationAction</p><p><b>status</b>: active</p><p><b>experimental</b>: true</p><p><b>subject</b>: Patient <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-fhir-types.html">All FHIR Types</a>#Patient)</span></p><p><b>publisher</b>: CPGonEBMonFHIR</p><p><b>description</b>: A drug administration that should be performed.</p><p><b>kind</b>: MedicationRequest</p><p><b>code</b>: Administration of substance (procedure) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#432102000)</span></p><p><b>product</b>: Dexamethasone (substance) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#372584003; atc#C05AA09 "Dexamethason")</span></p><blockquote><p><b>dosage</b></p><blockquote><p><b>Dosage Condition</b></p><blockquote><p><b>url</b></p><code>type</code></blockquote><p><b>value</b>: Body weight <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://loinc.org/">LOINC</a>#29463-7)</span></p><blockquote><p><b>url</b></p><code>value</code></blockquote><p><b>value</b>: ?-70</p></blockquote><p><b>timing</b>: Count 10 times, Duration 10days , Once per 1 days</p><p><b>route</b>: Oral route <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#26643006)</span></p><blockquote><p><b>doseAndRate</b></p></blockquote></blockquote></div>
</text>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeCapability">
<valueCode value="computable"/>
</extension>
<extension
url="http://hl7.org/fhir/uv/cpg/StructureDefinition/cpg-knowledgeRepresentationLevel">
<valueCode value="structured"/>
</extension>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-action/drug-administration-example"/>
<version value="1.0"/>
<name value="DrugAdministrationAction"/>
<status value="active"/>
<experimental value="true"/>
<subjectCodeableConcept>
<coding>
<system value="http://hl7.org/fhir/fhir-types"/>
<code value="Patient"/>
</coding>
</subjectCodeableConcept>
<publisher value="CPGonEBMonFHIR"/>
<description value="A drug administration that should be performed."/>
<kind value="MedicationRequest"/>
<code>
<coding>
<system value="http://snomed.info/sct"/>
<code value="432102000"/>
<display value="Administration of substance (procedure)"/>
</coding>
</code>
<productCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="372584003"/>
<display value="Dexamethasone (substance)"/>
</coding>
<coding>
<system value="http://fhir.de/CodeSystem/bfarm/atc"/>
<code value="C05AA09"/>
<display value="Dexamethason"/>
</coding>
</productCodeableConcept>
<dosage>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-dosage-condition">
<extension url="type">
<valueCodeableConcept>
<coding>
<system value="http://loinc.org"/>
<code value="29463-7"/>
<display value="Body weight"/>
</coding>
</valueCodeableConcept>
</extension>
<extension url="value">
<valueRange>
<high>
<value value="70"/>
<unit value="kg"/>
<system value="http://unitsofmeasure.org"/>
<code value="kg"/>
</high>
</valueRange>
</extension>
</extension>
<timing>
<repeat>
<count value="10"/>
<duration value="10"/>
<durationUnit value="d"/>
<frequency value="1"/>
<period value="1"/>
<periodUnit value="d"/>
</repeat>
</timing>
<route>
<coding>
<system value="http://snomed.info/sct"/>
<code value="26643006"/>
<display value="Oral route"/>
</coding>
</route>
<doseAndRate>
<doseQuantity>
<value value="6"/>
<unit value="mg"/>
<system value="http://unitsofmeasure.org"/>
<code value="mg"/>
</doseQuantity>
<rateQuantity>
<value value="1"/>
<unit value="/d"/>
<system value="http://unitsofmeasure.org"/>
<code value="/d"/>
</rateQuantity>
</doseAndRate>
</dosage>
</ActivityDefinition>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/population"/>
<resource>
<EvidenceVariable>
<id value="ExampleRecommendationEligibilityCriteria"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_ExampleRecommendationEligibilityCriteria"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="ExampleRecommendationEligibilityCriteria"> </a><a name="hcExampleRecommendationEligibilityCriteria"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "ExampleRecommendationEligibilityCriteria" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-eligibility-criteria.html">Recommendation Eligibility Criteria</a></p></div><p><b>url</b>: <code>https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria</code></p><p><b>name</b>: PopulationExample</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote></div>
</text>
<url
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria"/>
<name value="PopulationExample"/>
<status value="active"/>
<characteristic>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="840539006"/>
<display
value="Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
</characteristic>
</EvidenceVariable>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-justification"/>
<resource>
<ArtifactAssessment>
<id value="ExampleRecommendationJustification"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-justification"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ArtifactAssessment_ExampleRecommendationJustification"> </a><p><b>Generated Narrative: ArtifactAssessment</b><a name="ExampleRecommendationJustification"> </a><a name="hcExampleRecommendationJustification"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceArtifactAssessment "ExampleRecommendationJustification" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-justification.html">Recommendation Justification</a></p></div><p><b>ArtifactAssessment Version</b>: 0.1.0</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2020-01-03</p><p><b>artifact</b>: See on this page: PlanDefinition/ExampleRecommendationPlan</p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Strength of recommendation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#strength)</span></p><p><b>classifier</b>: Strong for an intervention <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-cs-recommendation-strength.html">Recommendation Strength</a>#strong-for)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Overall certainty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Overall)</span></p><p><b>classifier</b>: Very low quality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#very-low)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Consensus <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#consensus)</span></p><p><b>classifier</b>: Strong <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-recommendation-strength.html">StrengthOfRecommendationRating</a>#strong)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: container</p><p><b>type</b>: Certainty of evidence rating <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#certainty-of-evidence-rating)</span></p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>justification</td><td>Certainty of evidence rating <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#certainty-of-evidence-rating)</span></td><td>See on this page: ArtifactAssessment/ExampleCertaintyOfEvidenceRating</td></tr></table></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: container</p><p><b>type</b>: Net effect <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#net-effect)</span></p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>supported-with</td><td>Net effect <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#net-effect)</span></td><td>See on this page: Evidence/ExampleNetEffectEstimate</td></tr></table></blockquote></div>
</text>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version">
<valueString value="0.1.0"/>
</extension>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status">
<valueCode value="active"/>
</extension>
<date value="2020-01-03"/>
<artifactReference>🔗
<reference value="PlanDefinition/ExampleRecommendationPlan"/>
</artifactReference>
<content>
<informationType value="rating"/>
<type>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="strength"/>
<display value="Strength of recommendation"/>
</coding>
</type>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-cs-recommendation-strength"/>
<code value="strong-for"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Overall"/>
<display value="Overall certainty"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="very-low"/>
<display value="Very low quality"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="consensus"/>
<display value="Consensus"/>
</coding>
</type>
<classifier>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/recommendation-strength"/>
<code value="strong"/>
<display value="Strong"/>
</coding>
</classifier>
</content>
<content>
<informationType value="container"/>
<type>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="certainty-of-evidence-rating"/>
<display value="Certainty of evidence rating"/>
</coding>
</type>
<relatedArtifact>
<type value="justification"/>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="certainty-of-evidence-rating"/>
<display value="Certainty of evidence rating"/>
</coding>
</classifier>
<resourceReference>🔗
<reference
value="ArtifactAssessment/ExampleCertaintyOfEvidenceRating"/>
</resourceReference>
</relatedArtifact>
</content>
<content>
<informationType value="container"/>
<type>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="net-effect"/>
<display value="Net effect"/>
</coding>
</type>
<relatedArtifact>
<type value="supported-with"/>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="net-effect"/>
<display value="Net effect"/>
</coding>
</classifier>
<resourceReference>🔗
<reference value="Evidence/ExampleNetEffectEstimate"/>
</resourceReference>
</relatedArtifact>
</content>
</ArtifactAssessment>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/certainty-of-evidence-rating"/>
<resource>
<ArtifactAssessment>
<id value="ExampleCertaintyOfEvidenceRating"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/certainty-of-evidence-rating"/>
</meta>
<text>
<status value="extensions"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="ArtifactAssessment_ExampleCertaintyOfEvidenceRating"> </a><p><b>Generated Narrative: ArtifactAssessment</b><a name="ExampleCertaintyOfEvidenceRating"> </a><a name="hcExampleCertaintyOfEvidenceRating"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceArtifactAssessment "ExampleCertaintyOfEvidenceRating" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-certainty-of-evidence-rating.html">Certainty of Evidence Rating</a></p></div><p><b>ArtifactAssessment Version</b>: 0.1.1</p><p><b>ArtifactAssessment Publication Status</b>: active</p><p><b>date</b>: 2022-03-11</p><p><b>artifact</b>: See on this page: Evidence/ExampleStudyOutcomeEvidence</p><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Overall certainty <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Overall)</span></p><p><b>classifier</b>: Moderate quality <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#moderate)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Risk of bias <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#RiskOfBias)</span></p><p><b>classifier</b>: serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#serious-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Imprecision <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#Imprecision)</span></p><p><b>classifier</b>: serious concern <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#serious-concern)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Large effect <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#LargeEffect)</span></p><p><b>classifier</b>: increase rating: +2 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#upcode2)</span></p></blockquote><blockquote><p><b>content</b></p><p><b>informationType</b>: rating</p><p><b>type</b>: Plausible confounding <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-certainty-type.html">Evidence Certainty Type</a>#PlausibleConfounding)</span></p><p><b>classifier</b>: increase rating: +1 <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-certainty-rating.html">Evidence Certainty Rating</a>#upcode1)</span></p></blockquote></div>
</text>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-version">
<valueString value="0.1.1"/>
</extension>
<extension
url="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ceosys-extension-artifact-assessment-publication-status">
<valueCode value="active"/>
</extension>
<date value="2022-03-11"/>
<artifactReference>🔗
<reference value="Evidence/ExampleStudyOutcomeEvidence"/>
</artifactReference>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Overall"/>
<display value="Overall certainty"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="moderate"/>
<display value="Moderate quality"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="RiskOfBias"/>
<display value="Risk of bias"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="Imprecision"/>
<display value="Imprecision"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="serious-concern"/>
<display value="serious concern"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="LargeEffect"/>
<display value="Large effect"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="upcode2"/>
<display value="increase rating: +2"/>
</coding>
</classifier>
</content>
<content>
<informationType value="rating"/>
<type>
<coding>
<system value="http://hl7.org/fhir/certainty-type"/>
<code value="PlausibleConfounding"/>
<display value="Plausible confounding"/>
</coding>
</type>
<classifier>
<coding>
<system value="http://hl7.org/fhir/certainty-rating"/>
<code value="upcode1"/>
<display value="increase rating: +1"/>
</coding>
</classifier>
</content>
</ArtifactAssessment>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-outcome-evidence"/>
<resource>
<Evidence>
<id value="ExampleStudyOutcomeEvidence"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-outcome-evidence"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Evidence_ExampleStudyOutcomeEvidence"> </a><p><b>Generated Narrative: Evidence</b><a name="ExampleStudyOutcomeEvidence"> </a><a name="hcExampleStudyOutcomeEvidence"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidence "ExampleStudyOutcomeEvidence" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-study-outcome-evidence.html">Study Outcome Evidence</a></p></div><p><b>name</b>: ExampleStudyOutcomeEvidence</p><p><b>status</b>: active</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td>See on this page: Citation/ExampleStudyCitation</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href="Group-ExampleStudyCohort.html">Group/ExampleStudyCohort</a></p><p><b>intended</b>: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: See on this page: EvidenceVariable/ExampleOutcome</p></blockquote><p><b>synthesisType</b>: not applicable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-synthesis-type.html">SynthesisType</a>#NotApplicable)</span></p></div>
</text>
<name value="ExampleStudyOutcomeEvidence"/>
<status value="active"/>
<relatedArtifact>
<type value="citation"/>
<resourceReference>🔗
<reference value="Citation/ExampleStudyCitation"/>
</resourceReference>
</relatedArtifact>
<variableDefinition>
<variableRole>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/variable-role"/>
<code value="population"/>
</coding>
</variableRole>
<observed>🔗
<reference value="Group/ExampleStudyCohort"/>
</observed>
<intended>🔗
<reference
value="EvidenceVariable/ExampleStudyEligibilityCriteria"/>
</intended>
</variableDefinition>
<variableDefinition>
<variableRole>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/variable-role"/>
<code value="measuredVariable"/>
</coding>
</variableRole>
<observed>🔗
<reference value="EvidenceVariable/ExampleOutcome"/>
</observed>
</variableDefinition>
<synthesisType>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/synthesis-type"/>
<code value="NotApplicable"/>
</coding>
</synthesisType>
</Evidence>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome-evidence-synthesis"/>
<resource>
<Evidence>
<id value="ExampleOutcomeEvidenceSynthesis"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-evidence-synthesis"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Evidence_ExampleOutcomeEvidenceSynthesis"> </a><p><b>Generated Narrative: Evidence</b><a name="ExampleOutcomeEvidenceSynthesis"> </a><a name="hcExampleOutcomeEvidenceSynthesis"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidence "ExampleOutcomeEvidenceSynthesis" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-outcome-evidence-synthesis.html">Outcome Evidence Synthesis</a></p></div><p><b>name</b>: ExampleOutcomeEvidenceSynthesis</p><p><b>status</b>: active</p><h3>RelatedArtifacts</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>ResourceReference</b></td></tr><tr><td style="display: none">*</td><td>citation</td><td>See on this page: Citation/ExampleStudyCitation</td></tr></table><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: population <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#population)</span></p><p><b>observed</b>: <a href="Group-ExampleEvidenceSynthesisCohorts.html">Group/ExampleEvidenceSynthesisCohorts</a></p><p><b>intended</b>: See on this page: EvidenceVariable/ExampleStudyEligibilityCriteria</p></blockquote><blockquote><p><b>variableDefinition</b></p><p><b>variableRole</b>: measured variable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#measuredVariable)</span></p><p><b>observed</b>: See on this page: EvidenceVariable/ExampleOutcome</p></blockquote><p><b>synthesisType</b>: not applicable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-synthesis-type.html">SynthesisType</a>#NotApplicable)</span></p></div>
</text>
<name value="ExampleOutcomeEvidenceSynthesis"/>
<status value="active"/>
<relatedArtifact>
<type value="citation"/>
<resourceReference>🔗
<reference value="Citation/ExampleStudyCitation"/>
</resourceReference>
</relatedArtifact>
<variableDefinition>
<variableRole>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/variable-role"/>
<code value="population"/>
</coding>
</variableRole>
<observed>🔗
<reference value="Group/ExampleEvidenceSynthesisCohorts"/>
</observed>
<intended>🔗
<reference
value="EvidenceVariable/ExampleStudyEligibilityCriteria"/>
</intended>
</variableDefinition>
<variableDefinition>
<variableRole>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/variable-role"/>
<code value="measuredVariable"/>
</coding>
</variableRole>
<observed>🔗
<reference value="EvidenceVariable/ExampleOutcome"/>
</observed>
</variableDefinition>
<synthesisType>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/synthesis-type"/>
<code value="NotApplicable"/>
</coding>
</synthesisType>
</Evidence>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-eligbility-criteria"/>
<resource>
<EvidenceVariable>
<id value="ExampleStudyEligibilityCriteria"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-eligibility-criteria"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_ExampleStudyEligibilityCriteria"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="ExampleStudyEligibilityCriteria"> </a><a name="hcExampleStudyEligibilityCriteria"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "ExampleStudyEligibilityCriteria" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-study-eligibility-criteria.html">Study Eligibility Criteria</a></p></div><p><b>name</b>: ExampleStudyEligibilityCriteria</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Clinical finding (finding) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#404684003)</span></td><td>Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#840539006)</span></td></tr></table></blockquote></div>
</text>
<name value="ExampleStudyEligibilityCriteria"/>
<status value="active"/>
<characteristic>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="404684003"/>
<display value="Clinical finding (finding)"/>
</coding>
</type>
<valueCodeableConcept>
<coding>
<system value="http://snomed.info/sct"/>
<code value="840539006"/>
<display
value="Disease caused by Severe acute respiratory syndrome coronavirus 2 (disorder)"/>
</coding>
</valueCodeableConcept>
</definitionByTypeAndValue>
</characteristic>
</EvidenceVariable>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/study-citation"/>
<resource>
<Citation>
<id value="ExampleStudyCitation"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/study-citation"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Citation_ExampleStudyCitation"> </a><p><b>Generated Narrative: Citation</b><a name="ExampleStudyCitation"> </a><a name="hcExampleStudyCitation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceCitation "ExampleStudyCitation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-study-citation.html">Study Citation</a></p></div><p><b>name</b>: ExampleCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Titles</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Text</b></td></tr><tr><td style="display: none">*</td><td>Example Citation</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style="display: none">*</td><td>Publication Type <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Journal Article <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-citation-artifact-classifier.html">Citation Artifact Classifier</a>#D016428)</span></td></tr></table></blockquote></div>
</text>
<name value="ExampleCitation"/>
<status value="active"/>
<citedArtifact>
<identifier>
<value value="ceoysy/exampleIdentifier"/>
</identifier>
<title>
<text value="Example Citation"/>
</title>
<classification>
<type>
<coding>
<system
value="http://hl7.org/fhir/cited-artifact-classification-type"/>
<code value="publication-type"/>
<display value="Publication Type"/>
</coding>
</type>
<classifier>
<coding>
<system
value="http://hl7.org/fhir/citation-artifact-classifier"/>
<code value="D016428"/>
<display value="Journal Article"/>
</coding>
</classifier>
</classification>
</citedArtifact>
</Citation>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/outcome"/>
<resource>
<EvidenceVariable>
<id value="ExampleOutcome"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/outcome-definition"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="EvidenceVariable_ExampleOutcome"> </a><p><b>Generated Narrative: EvidenceVariable</b><a name="ExampleOutcome"> </a><a name="hcExampleOutcome"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidenceVariable "ExampleOutcome" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-outcome-definition.html">Outcome Definition</a></p></div><p><b>identifier</b>: <code>https://www.ceosys.de</code>/outcome-example</p><p><b>name</b>: Mortality</p><p><b>status</b>: active</p><blockquote><p><b>characteristic</b></p><p><b>exclude</b>: false</p><h3>DefinitionByTypeAndValues</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Value[x]</b></td></tr><tr><td style="display: none">*</td><td>Mortality rate (observable entity) <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="https://browser.ihtsdotools.org/">SNOWMED CT</a>#409651001)</span></td><td> percent<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></td></tr></table></blockquote><p><b>handling</b>: dichotomous</p></div>
</text>
<identifier>
<system value="https://www.ceosys.de"/>
<value value="outcome-example"/>
</identifier>
<name value="Mortality"/>
<status value="active"/>
<characteristic>
<exclude value="false"/>
<definitionByTypeAndValue>
<type>
<coding>
<system value="http://snomed.info/sct"/>
<code value="409651001"/>
<display value="Mortality rate (observable entity)"/>
</coding>
</type>
<valueQuantity>
<unit value="percent"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</valueQuantity>
</definitionByTypeAndValue>
</characteristic>
<handling value="dichotomous"/>
</EvidenceVariable>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/recommendation-citation"/>
<resource>
<Citation>
<id value="ExampleRecommendationCitation"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-citation"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Citation_ExampleRecommendationCitation"> </a><p><b>Generated Narrative: Citation</b><a name="ExampleRecommendationCitation"> </a><a name="hcExampleRecommendationCitation"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceCitation "ExampleRecommendationCitation" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-recommendation-citation.html">Recommendation Citation</a></p></div><p><b>name</b>: ExampleRecommendationCitation</p><p><b>status</b>: active</p><blockquote><p><b>citedArtifact</b></p><p><b>identifier</b>: ceoysy/exampleIdentifier</p><h3>Versions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Value</b></td></tr><tr><td style="display: none">*</td><td>1.0-alpha1</td></tr></table><p><b>currentState</b>: Archived <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-status-type.html">Cited Artifact Status Type</a>#archived)</span></p><h3>Titles</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Text</b></td></tr><tr><td style="display: none">*</td><td>Example Citation</td></tr></table><h3>Classifications</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Classifier</b></td></tr><tr><td style="display: none">*</td><td>Publication Type <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://hl7.org/fhir/R5/codesystem-cited-artifact-classification-type.html">Cited Artifact Classification Type</a>#publication-type)</span></td><td>Clinical practice guideline recommendation <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#guideline-recommendation)</span></td></tr></table></blockquote></div>
</text>
<name value="ExampleRecommendationCitation"/>
<status value="active"/>
<citedArtifact>
<identifier>
<value value="ceoysy/exampleIdentifier"/>
</identifier>
<version>
<value value="1.0-alpha1"/>
</version>
<currentState>
<coding>
<system value="http://hl7.org/fhir/cited-artifact-status-type"/>
<code value="archived"/>
<display value="Archived"/>
</coding>
</currentState>
<title>
<text value="Example Citation"/>
</title>
<classification>
<type>
<coding>
<system
value="http://hl7.org/fhir/cited-artifact-classification-type"/>
<code value="publication-type"/>
<display value="Publication Type"/>
</coding>
</type>
<classifier>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="guideline-recommendation"/>
<display value="Clinical practice guideline recommendation"/>
</coding>
</classifier>
</classification>
</citedArtifact>
</Citation>
</resource>
</entry>
<entry>
<fullUrl
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/guidelines/guideline-example/net-effect-estimate"/>
<resource>
<Evidence>
<id value="ExampleNetEffectEstimate"/>
<meta>
<profile
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/net-effect-estimate"/>
</meta>
<text>
<status value="generated"/>
<div xmlns="http://www.w3.org/1999/xhtml"><a name="Evidence_ExampleNetEffectEstimate"> </a><p><b>Generated Narrative: Evidence</b><a name="ExampleNetEffectEstimate"> </a><a name="hcExampleNetEffectEstimate"> </a></p><div style="display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%"><p style="margin-bottom: 0px">ResourceEvidence "ExampleNetEffectEstimate" </p><p style="margin-bottom: 0px">Profile: <a href="StructureDefinition-net-effect-estimate.html">Net Effect Estimate</a></p></div><p><b>name</b>: NetEffectExample</p><p><b>status</b>: unknown</p><h3>VariableDefinitions</h3><table class="grid"><tr><td style="display: none">-</td><td><b>VariableRole</b></td><td><b>Intended</b></td></tr><tr><td style="display: none">*</td><td>measured variable <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-variable-role.html">EvidenceVariableRole</a>#measuredVariable)</span></td><td>See on this page: EvidenceVariable/ExampleOutcome</td></tr></table><blockquote><p><b>statistic</b></p><p><b>description</b>: Net Effect</p><p><b>statisticType</b>: Net Effect <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#net-effect)</span></p><p><b>quantity</b>: 1.7 %<span style="background: LightGoldenRodYellow"> (Details: UCUM code % = '%')</span></p><h3>AttributeEstimates</h3><table class="grid"><tr><td style="display: none">-</td><td><b>Type</b></td><td><b>Level</b></td><td><b>Range</b></td></tr><tr><td style="display: none">*</td><td>Confidence interval <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="http://terminology.hl7.org/5.5.0/CodeSystem-attribute-estimate-type.html">StatisticAttribute Estimate Type</a>#C53324)</span></td><td>0.95</td><td>1.5-1.9</td></tr></table><blockquote><p><b>modelCharacteristic</b></p><p><b>code</b>: Relative importance weighting for use in weighted linear combinations <span style="background: LightGoldenRodYellow; margin: 4px; border: 1px solid khaki"> (<a href="CodeSystem-ceosys-code-system.html">CEOsys Code System</a>#relative-importance-weighting)</span></p><p><b>value</b>: 1</p><h3>Variables</h3><table class="grid"><tr><td style="display: none">-</td><td><b>VariableDefinition</b></td></tr><tr><td style="display: none">*</td><td>See on this page: EvidenceVariable/ExampleOutcome</td></tr></table></blockquote></blockquote></div>
</text>
<name value="NetEffectExample"/>
<status value="unknown"/>
<variableDefinition>
<variableRole>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/variable-role"/>
<code value="measuredVariable"/>
</coding>
</variableRole>
<intended>🔗
<reference value="EvidenceVariable/ExampleOutcome"/>
</intended>
</variableDefinition>
<statistic>
<description value="Net Effect"/>
<statisticType>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="net-effect"/>
<display value="Net Effect"/>
</coding>
</statisticType>
<quantity>
<value value="1.7"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</quantity>
<attributeEstimate>
<type>
<coding>
<system
value="http://terminology.hl7.org/CodeSystem/attribute-estimate-type"/>
<code value="C53324"/>
<display value="Confidence interval"/>
</coding>
</type>
<level value="0.95"/>
<range>
<low>
<value value="1.5"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</low>
<high>
<value value="1.9"/>
<system value="http://unitsofmeasure.org"/>
<code value="%"/>
</high>
</range>
</attributeEstimate>
<modelCharacteristic>
<code>
<coding>
<system
value="https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/CodeSystem/ceosys-code-system"/>
<code value="relative-importance-weighting"/>
</coding>
</code>
<value>
<value value="1"/>
</value>
<variable>
<variableDefinition>🔗
<reference value="EvidenceVariable/ExampleOutcome"/>
</variableDefinition>
</variable>
</modelCharacteristic>
</statistic>
</Evidence>
</resource>
</entry>
</Bundle>
IG © 2021+ Universitätsmedizin Greifswald. Package de.netzwerk-universitaetsmedizin.ebm-cpg#0.8.0-snapshot based on FHIR 5.0.0. Generated 2024-05-15
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