Eligibility Criteria - Definitions - Clinical Practice Guidelines (CPG) on EBMonFHIR v1.2.0

This page is part of the CPG-on-EBMonFHIR Implementation Guide (1.2.0).

Resource Profile: EligibilityCriteria - Detailed Descriptions

Draft as of 2022-05-15

Definitions for the eligibility-criteria resource profile.

Differential Elements Table
Key Elements Table
Snapshot Elements Table

Guidance on how to interpret the contents of this table can be found here

0. EvidenceVariable
2. EvidenceVariable.characteristic
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
4. EvidenceVariable.characteristic.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
6. EvidenceVariable.characteristic.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
8. EvidenceVariable.characteristic.definitionByTypeAndValue
10. EvidenceVariable.characteristic.definitionByTypeAndValue.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
12. EvidenceVariable.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
14. EvidenceVariable.characteristic.definitionByTypeAndValue.type
16. EvidenceVariable.characteristic.definitionByTypeAndValue.type.coding
Control	1..1
Must Support	true
18. EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
20. EvidenceVariable.characteristic.definitionByCombination
22. EvidenceVariable.characteristic.definitionByCombination.characteristic
Type	BackboneElement
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
24. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
26. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
28. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
30. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
32. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
34. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
36. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Control	1..1
Must Support	true
38. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
40. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination
42. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Type	BackboneElement
Must Support	true
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
44. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
46. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
48. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
50. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
52. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
54. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
56. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Control	1..1
Must Support	true
58. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
60. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
62. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Type	BackboneElement
Must Support	true
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
64. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
66. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
68. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
70. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
72. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
74. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
76. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Control	1..1
Must Support	true
78. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
80. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
82. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Type	BackboneElement
Must Support	true
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
84. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
86. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
88. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
90. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
92. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
94. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
96. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Control	1..1
Must Support	true
98. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
100. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Control	0..*
102. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
104. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Control	1..?
106. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
108. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
110. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
112. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
114. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
116. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Control	0..0
118. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Control	0..*
120. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
122. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Control	1..?
124. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
126. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
128. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
130. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
132. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
134. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Control	0..0
136. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Control	0..*
138. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
140. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Control	1..?
142. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
144. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
146. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
148. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
150. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
152. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Control	0..0
154. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Control	0..*
156. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
158. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Control	1..?
160. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
162. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
164. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
166. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
168. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
170. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Control	0..0
172. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Control	0..*
174. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
176. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Control	1..?
178. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
180. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
182. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
184. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
186. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
188. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Control	0..0
190. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Control	0..*
192. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
194. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Control	1..?
196. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
198. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
200. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Control	0..0
202. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Control	0..*
204. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
206. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Control	1..?
208. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
210. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
212. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
214. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
216. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
218. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Control	0..0
220. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Control	0..*
222. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
224. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Control	1..?
226. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
228. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
230. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Control	0..0
232. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Control	0..*
234. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
236. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Control	1..?
238. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
240. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
242. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
244. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
246. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
248. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
250. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Control	0..0
252. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Control	0..*
254. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
256. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Control	1..?
258. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
260. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
262. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
264. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
266. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
268. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Control	0..0
271. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Control	0..*
273. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
275. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Control	1..?
277. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
279. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
281. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
283. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
285. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
287. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Control	0..0
290. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Control	0..*
292. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
294. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Control	1..?
296. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
298. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
300. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
302. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
304. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
306. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Control	0..0
309. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Control	0..*
311. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
313. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Control	1..?
315. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
317. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
319. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
321. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
323. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
325. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Control	0..0
328. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Control	0..*
330. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
332. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Control	1..?
334. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
336. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
338. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
340. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
342. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
344. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Control	0..0
347. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Control	0..*
349. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
351. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Control	1..?
353. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
355. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
357. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Control	0..0
360. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Control	0..*
362. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
364. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Control	1..?
366. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
368. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
370. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
372. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
374. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
376. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Control	0..0
379. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Control	0..*
381. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
383. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Control	1..?
385. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
387. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
389. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Control	0..0
392. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Control	0..*
394. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
396. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Control	1..?
398. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
400. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
402. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
404. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
406. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
408. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
410. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Control	0..0
413. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Control	0..*
415. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
417. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Control	1..?
419. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
421. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
423. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
425. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
427. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
429. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Control	0..0
432. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Control	0..*
434. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
436. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Control	1..?
438. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
440. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
442. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
444. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
446. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
448. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Control	0..0
451. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Control	0..*
453. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
455. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Control	1..?
457. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
459. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
461. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
463. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
465. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
467. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Control	0..0
470. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Control	0..*
472. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
474. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Control	1..?
476. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
478. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
480. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
482. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
484. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
486. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Control	0..0
489. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Control	0..*
491. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
493. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Control	1..?
495. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
497. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
499. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
501. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
503. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
505. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Control	0..0
508. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Control	0..*
510. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
512. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Control	1..?
514. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
516. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
518. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Control	0..0
521. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Control	0..*
523. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
525. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Control	1..?
527. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
529. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
531. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
533. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
535. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
537. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Control	0..0
540. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Control	0..*
542. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
544. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Control	1..?
546. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
548. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
550. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Control	0..0
553. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Control	0..*
555. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
557. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Control	1..?
559. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
561. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
563. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
565. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
567. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
569. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
571. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Control	0..0
574. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Control	0..*
576. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
578. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Control	1..?
580. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
582. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
584. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
586. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
588. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
590. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Control	0..0
593. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Control	0..*
595. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
597. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Control	1..?
599. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
601. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
603. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
605. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
607. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
609. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Control	0..0
612. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Control	0..*
614. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
616. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Control	1..?
618. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
620. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
622. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
624. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
626. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
628. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Control	0..0
631. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Control	0..*
633. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
635. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Control	1..?
637. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
639. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
641. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
643. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
645. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
647. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Control	0..0
650. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Control	0..*
652. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
654. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Control	1..?
656. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
658. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
660. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
662. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
664. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
666. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Control	0..0
669. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Control	0..*
671. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
673. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Control	1..?
675. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
677. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
679. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Control	0..0
682. EvidenceVariable.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Control	0..*
684. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
686. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Control	1..?
688. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
690. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
692. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
694. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
696. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
698. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Control	0..0
701. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Control	0..*
703. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
705. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Control	1..?
707. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
709. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
711. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Control	0..0
714. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Control	0..*
716. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
718. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Control	1..?
720. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
722. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
724. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
726. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
728. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
730. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
732. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Control	0..0
735. EvidenceVariable.characteristic:condition
Slice Name	condition
Control	0..*
737. EvidenceVariable.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
739. EvidenceVariable.characteristic:condition.definitionByTypeAndValue
Control	1..?
741. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
743. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
745. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
747. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
749. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
751. EvidenceVariable.characteristic:condition.definitionByCombination
Control	0..0
753. EvidenceVariable.characteristic:allergy
Slice Name	allergy
Control	0..*
755. EvidenceVariable.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
757. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue
Control	1..?
759. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
761. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
763. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
765. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
767. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
769. EvidenceVariable.characteristic:allergy.definitionByCombination
Control	0..0
771. EvidenceVariable.characteristic:radiologyFinding
Slice Name	radiologyFinding
Control	0..*
773. EvidenceVariable.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
775. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue
Control	1..?
777. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
779. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
781. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
783. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
785. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
787. EvidenceVariable.characteristic:radiologyFinding.definitionByCombination
Control	0..0
789. EvidenceVariable.characteristic:episodeOfCare
Slice Name	episodeOfCare
Control	0..*
791. EvidenceVariable.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
793. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue
Control	1..?
795. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
797. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
799. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
801. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
803. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
805. EvidenceVariable.characteristic:episodeOfCare.definitionByCombination
Control	0..0
807. EvidenceVariable.characteristic:procedure
Slice Name	procedure
Control	0..*
809. EvidenceVariable.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
811. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue
Control	1..?
813. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
815. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
817. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
819. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
821. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
823. EvidenceVariable.characteristic:procedure.definitionByCombination
Control	0..0
825. EvidenceVariable.characteristic:assessmentScale
Slice Name	assessmentScale
Control	0..*
827. EvidenceVariable.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
829. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue
Control	1..?
831. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
833. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
835. EvidenceVariable.characteristic:assessmentScale.definitionByCombination
Control	0..0
837. EvidenceVariable.characteristic:device
Slice Name	device
Control	0..*
839. EvidenceVariable.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
841. EvidenceVariable.characteristic:device.definitionByTypeAndValue
Control	1..?
843. EvidenceVariable.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
845. EvidenceVariable.characteristic:device.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
847. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
849. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
851. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
853. EvidenceVariable.characteristic:device.definitionByCombination
Control	0..0
855. EvidenceVariable.characteristic:observation
Slice Name	observation
Control	0..*
857. EvidenceVariable.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
859. EvidenceVariable.characteristic:observation.definitionByTypeAndValue
Control	1..?
861. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
863. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.type
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
865. EvidenceVariable.characteristic:observation.definitionByCombination
Control	0..0
867. EvidenceVariable.characteristic:drugAdministration
Slice Name	drugAdministration
Control	0..*
869. EvidenceVariable.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
871. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue
Control	1..?
873. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
875. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
877. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.type
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
879. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
881. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
883. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Control	1..1
Must Support	true
885. EvidenceVariable.characteristic:drugAdministration.definitionByCombination
Control	0..0

Guidance on how to interpret the contents of this table can be found here

0. EvidenceVariable
Definition	The EvidenceVariable resource describes an element that knowledge (Evidence) is about.
Short	A definition of an exposure, outcome, or other variable
Comments	The EvidenceVariable may be an exposure variable (intervention, condition, or state), a measured variable (outcome or observed parameter), or other variable (such as confounding factor).
Control	0..*
Is Modifier	false
Must Support	false
Summary	false
Invariants	cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation (name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$'))
2. EvidenceVariable.implicitRules
Definition	A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.
Short	A set of rules under which this content was created
Comments	Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.
Control	0..1
Type	uri
Is Modifier	true because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
4. EvidenceVariable.contained
Definition	These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.
Short	Contained, inline Resources
Comments	This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.
Control	0..* This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
Type	Resource
Is Modifier	false
Must Support	false
Summary	false
Alternate Names	inline resources, anonymous resources, contained resources
6. EvidenceVariable.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
Must Support	false
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
8. EvidenceVariable.name
Definition	A natural language name identifying the evidence variable. This name should be usable as an identifier for the module by machine processing applications such as code generation.
Short	Name for this evidence variable (computer friendly)
Comments	The name is not expected to be globally unique. The name should be a simple alphanumeric type name to ensure that it is machine-processing friendly.
Control	10..1 This element is affected by the following invariants: cnl-0
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	true
Summary	true
Requirements	Support human navigation and code generation.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
10. EvidenceVariable.status
Definition	The status of this evidence variable. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Comments	Allows filtering of evidence variables that are appropriate for use versus not. See guidance around (not) making local changes to elements here. Allows filtering of evidence variables that are appropriate for use versus not. See guidance around (not) making local changes to elements here.
Control	1..1
Binding	The codes SHALL be taken from PublicationStatushttp://hl7.org/fhir/ValueSet/publication-status\|5.0.0 (required to `http://hl7.org/fhir/ValueSet/publication-status\|5.0.0`) The lifecycle status of an artifact.
Type	code
Is Modifier	true because This is labeled as "Is Modifier" because applications should not use a retired {{title}} without due consideration
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
12. EvidenceVariable.characteristic
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	10..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
14. EvidenceVariable.characteristic.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
16. EvidenceVariable.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
18. EvidenceVariable.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
20. EvidenceVariable.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
22. EvidenceVariable.characteristic.definitionByTypeAndValue.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
24. EvidenceVariable.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
26. EvidenceVariable.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
28. EvidenceVariable.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
30. EvidenceVariable.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
32. EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
34. EvidenceVariable.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
36. EvidenceVariable.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
38. EvidenceVariable.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombinationhttp://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0 (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
40. EvidenceVariable.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
42. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
44. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
46. EvidenceVariable.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
48. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
50. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
52. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
54. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
56. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
58. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
60. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
62. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
64. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
66. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombinationhttp://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0 (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
68. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
70. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
72. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
74. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
76. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
78. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
80. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
82. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
84. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
86. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
88. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
90. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
92. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
94. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombinationhttp://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0 (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
96. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
98. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
100. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
102. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
104. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
106. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
108. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
110. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
112. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
114. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
116. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
118. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
120. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
122. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombinationhttp://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0 (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
124. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
126. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
128. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
130. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
132. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
134. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	ExtensionAdditional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
136. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
138. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
140. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
142. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
144. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range, boolean, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
146. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
148. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
150. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
152. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
154. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
156. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
158. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
160. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
162. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
164. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
166. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
171. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
173. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
175. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
177. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
179. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
181. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
183. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
185. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
187. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
189. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
191. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
196. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
198. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
200. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
202. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
204. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
206. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
208. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
210. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
212. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
214. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
216. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
221. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
223. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
225. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
227. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
229. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
231. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
233. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
235. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
237. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
239. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
241. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
246. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
248. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
250. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
252. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
254. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
256. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
258. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
260. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
262. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
264. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
266. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
271. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
273. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
275. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
277. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
279. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
281. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
283. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Assessment Scaleshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
285. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
287. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
292. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
294. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
296. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
298. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
300. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
302. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
304. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
306. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
308. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
310. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
312. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
317. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
319. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
321. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
323. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
325. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
327. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
329. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Observationshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
331. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
333. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
338. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
340. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
342. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
344. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
346. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
348. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
350. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
352. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
354. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
356. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
358. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
360. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
365. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
367. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
369. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
371. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
373. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
375. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
377. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
379. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
381. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
383. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
385. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
390. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
392. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
394. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
396. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
398. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
400. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
402. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
404. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
406. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
408. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
410. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
415. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
417. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
419. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
421. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
423. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
425. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
427. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
429. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
431. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
433. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
435. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
440. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
442. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
444. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
446. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
448. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
450. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
452. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
454. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
456. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
458. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
460. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
465. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
467. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
469. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
471. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
473. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
475. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
477. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
479. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
481. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
483. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
485. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
490. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
492. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
494. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
496. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
498. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
500. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
502. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Assessment Scaleshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
504. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
506. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
511. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
513. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
515. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
517. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
519. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
521. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
523. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
525. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
527. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
529. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
531. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
536. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
538. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
540. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
542. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
544. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
546. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
548. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Observationshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
550. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
552. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
557. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
559. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
561. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
563. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
565. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
567. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
569. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
571. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
573. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
575. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
577. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
579. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
584. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
586. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
588. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
590. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
592. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
594. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
596. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
598. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
600. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
602. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
604. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
609. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
611. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
613. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
615. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
617. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
619. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
621. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
623. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
625. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
627. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
629. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
634. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
636. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
638. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
640. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
642. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
644. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
646. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
648. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
650. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
652. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
654. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
659. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
661. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
663. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
665. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
667. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
669. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
671. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
673. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
675. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
677. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
679. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
684. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
686. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
688. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
690. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
692. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
694. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
696. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
698. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
700. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
702. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
704. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
709. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
711. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
713. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
715. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
717. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
719. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
721. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Assessment Scaleshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
723. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
725. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
730. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
732. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
734. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
736. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
738. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
740. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
742. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
744. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
746. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
748. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
750. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
755. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
757. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
759. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
761. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
763. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
765. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
767. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Observationshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
769. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
771. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
776. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
778. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
780. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
782. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
784. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
786. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
788. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
790. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
792. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
794. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
796. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
798. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
803. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
805. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
807. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
809. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
811. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
813. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
815. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
817. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
819. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
821. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
823. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
828. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
830. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
832. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
834. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
836. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
838. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
840. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
842. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
844. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
846. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
848. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
853. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
855. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
857. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
859. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
861. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
863. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
865. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
867. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
869. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
871. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
873. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
878. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
880. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
882. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
884. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
886. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
888. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
890. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
892. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
894. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
896. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
898. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
903. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
905. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
907. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
909. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
911. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
913. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
915. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
917. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
919. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
921. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
923. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
928. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
930. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
932. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
934. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
936. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
938. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
940. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Assessment Scaleshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
942. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
944. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
949. EvidenceVariable.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
951. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
953. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
955. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
957. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
959. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
961. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
963. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
965. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
967. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
969. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
974. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
976. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
978. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
980. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
982. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
984. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
986. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Observationshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
988. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
990. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
995. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	01..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
997. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
999. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1001. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1003. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1005. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1007. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions. Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1009. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1011. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1013. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1015. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1017. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1022. EvidenceVariable.characteristic:condition
Slice Name	condition
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1024. EvidenceVariable.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1026. EvidenceVariable.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1028. EvidenceVariable.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1030. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1032. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1034. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1036. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1038. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1040. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1042. EvidenceVariable.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1047. EvidenceVariable.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1049. EvidenceVariable.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1051. EvidenceVariable.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1053. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1055. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1057. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1059. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1061. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1063. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1065. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1067. EvidenceVariable.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1072. EvidenceVariable.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1074. EvidenceVariable.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1076. EvidenceVariable.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1078. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1080. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1082. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1084. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1086. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1088. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1090. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1092. EvidenceVariable.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1097. EvidenceVariable.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1099. EvidenceVariable.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1101. EvidenceVariable.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1103. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1105. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1107. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1109. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1111. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1113. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1115. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1117. EvidenceVariable.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1122. EvidenceVariable.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1124. EvidenceVariable.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1126. EvidenceVariable.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1128. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1130. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1132. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1134. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1136. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1138. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1140. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1142. EvidenceVariable.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1147. EvidenceVariable.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1149. EvidenceVariable.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1151. EvidenceVariable.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1153. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1155. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1157. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1159. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Assessment Scaleshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1161. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1163. EvidenceVariable.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1168. EvidenceVariable.characteristic:device
Slice Name	device
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1170. EvidenceVariable.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1172. EvidenceVariable.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1174. EvidenceVariable.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1176. EvidenceVariable.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1178. EvidenceVariable.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1180. EvidenceVariable.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1182. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1184. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1186. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1188. EvidenceVariable.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1193. EvidenceVariable.characteristic:observation
Slice Name	observation
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1195. EvidenceVariable.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1197. EvidenceVariable.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1199. EvidenceVariable.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1201. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1203. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1205. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from For example codes, see Observationshttp://terminology.hl7.org/ValueSet/usage-context-type (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1207. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1209. EvidenceVariable.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1214. EvidenceVariable.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination ((definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
1216. EvidenceVariable.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1218. EvidenceVariable.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1220. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	10..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1222. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1224. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1226. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count())) ext-1: Must have either extensions or value[x], not both (extension.exists() != value.exists())
1228. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextTypehttp://terminology.hl7.org/ValueSet/usage-context-type (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1230. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1232. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	01..1
Binding	Unless not suitable, these codes SHALL be taken from For codes, see Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept, boolean, Reference, Quantity, id, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1234. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	10..1*
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))
1236. EvidenceVariable.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..01 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (hasValue() or (children().count() > id.count()))

Guidance on how to interpret the contents of this table can be found here

0. EvidenceVariable
Definition	The EvidenceVariable resource describes an element that knowledge (Evidence) is about.
Short	A definition of an exposure, outcome, or other variable
Comments	The EvidenceVariable may be an exposure variable (intervention, condition, or state), a measured variable (outcome or observed parameter), or other variable (such as confounding factor).
Control	0..*
Is Modifier	false
Must Support	false
Summary	false
Invariants	cnl-0: Name should be usable as an identifier for the module by machine processing applications such as code generation (`name.exists() implies name.matches('^[A-Z]([A-Za-z0-9_]){1,254}$')`)
2. EvidenceVariable.id
Definition	The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes.
Short	Logical id of this artifact
Comments	Within the context of the FHIR RESTful interactions, the resource has an id except for cases like the create and conditional update. Otherwise, the use of the resouce id depends on the given use case.
Control	0..1
Type	id
Is Modifier	false
Must Support	false
Summary	true
4. EvidenceVariable.meta
Definition	The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content might not always be associated with version changes to the resource.
Short	Metadata about the resource
Control	0..1
Type	Meta
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
6. EvidenceVariable.implicitRules
Definition	A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content. Often, this is a reference to an implementation guide that defines the special rules along with other profiles etc.
Short	A set of rules under which this content was created
Comments	Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. Often, when used, the URL is a reference to an implementation guide that defines these special rules as part of its narrative along with other profiles, value sets, etc.
Control	0..1
Type	uri
Is Modifier	true because This element is labeled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies its meaning or interpretation
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
8. EvidenceVariable.language
Definition	The base language in which the resource is written.
Short	Language of the resource content
Comments	Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource. Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute).
Control	0..1
Binding	The codes SHALL be taken from AllLanguages (required to `http://hl7.org/fhir/ValueSet/all-languages\|5.0.0`) IETF language tag for a human language
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
10. EvidenceVariable.text
Definition	A human-readable narrative that contains a summary of the resource and can be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it "clinically safe" for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety.
Short	Text summary of the resource, for human interpretation
Comments	Contained resources do not have a narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a "text blob" or where text is additionally entered raw or narrated and encoded information is added later.
Control	0..1 This element is affected by the following invariants: dom-6
Type	Narrative
Is Modifier	false
Must Support	false
Summary	false
Alternate Names	narrative, html, xhtml, display
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
12. EvidenceVariable.contained
Definition	These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, nor can they have their own independent transaction scope. This is allowed to be a Parameters resource if and only if it is referenced by a resource that provides context/meaning.
Short	Contained, inline Resources
Comments	This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again. Contained resources may have profiles and tags in their meta elements, but SHALL NOT have security labels.
Control	0..* This element is affected by the following invariants: dom-2, dom-4, dom-3, dom-5
Type	Resource
Is Modifier	false
Must Support	false
Summary	false
Alternate Names	inline resources, anonymous resources, contained resources
14. EvidenceVariable.extension
Definition	May be used to represent additional information that is not part of the basic definition of the resource. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Must Support	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
16. EvidenceVariable.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the resource and that modifies the understanding of the element that contains it and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the resource that contains them
Must Support	false
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
18. EvidenceVariable.url
Definition	An absolute URI that is used to identify this evidence variable when it is referenced in a specification, model, design or an instance; also called its canonical identifier. This SHOULD be globally unique and SHOULD be a literal address at which an authoritative instance of this evidence variable is (or will be) published. This URL can be the target of a canonical reference. It SHALL remain the same when the evidence variable is stored on different servers.
Short	Canonical identifier for this evidence variable, represented as a URI (globally unique)
Comments	In some cases, the resource can no longer be found at the stated url, but the url itself cannot change. Implementations can use the meta.source element to indicate where the current master source of the resource can be found.
Control	0..1
Type	uri
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Requirements	Allows the evidence variable to be referenced by a single globally unique identifier.
Invariants	cnl-1: URL should not contain \| or # - these characters make processing canonical references problematic (`exists() implies matches('^[^\|# ]+$')`) ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
20. EvidenceVariable.identifier
Definition	A formal identifier that is used to identify this evidence variable when it is represented in other formats, or referenced in a specification, model, design or an instance.
Short	Additional identifier for the evidence variable
Comments	Typically, this is used for identifiers that can go in an HL7 V3 II (instance identifier) data type, and can then identify this evidence variable outside of FHIR, where it is not possible to use the logical URI.
Note	This is a business identifier, not a resource identifier (see discussion)
Control	0..*
Type	Identifier
Is Modifier	false
Must Support	false
Summary	true
Requirements	Allows externally provided and/or usable business identifiers to be easily associated with the module.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
22. EvidenceVariable.version
Definition	The identifier that is used to identify this version of the evidence variable when it is referenced in a specification, model, design or instance. This is an arbitrary value managed by the evidence variable author and is not expected to be globally unique. For example, it might be a timestamp (e.g. yyyymmdd) if a managed version is not available. There is also no expectation that versions can be placed in a lexicographical sequence. To provide a version consistent with the Decision Support Service specification, use the format Major.Minor.Revision (e.g. 1.0.0). For more information on versioning knowledge assets, refer to the Decision Support Service specification. Note that a version is required for non-experimental active artifacts.
Short	Business version of the evidence variable
Comments	There may be different evidence variable instances that have the same identifier but different versions. The version can be appended to the url in a reference to allow a reference to a particular business version of the evidence variable with the format [url]\|[version]. The version SHOULD NOT contain a '#' - see Business Version.
Note	This is a business version Id, not a resource version Id (see discussion)
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
24. EvidenceVariable.versionAlgorithm[x]
Definition	Indicates the mechanism used to compare versions to determine which is more current.
Short	How to compare versions
Comments	If set as a string, this is a FHIRPath expression that has two additional context variables passed in - %version1 and %version2 and will return a negative number if version1 is newer, a positive number if version2 is newer, and a 0 if the version ordering can't successfully be determined.
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from VersionAlgorithm (extensible to `http://hl7.org/fhir/ValueSet/version-algorithm`)
Type	Choice of: string, Coding
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
26. EvidenceVariable.name
Definition	A natural language name identifying the evidence variable. This name should be usable as an identifier for the module by machine processing applications such as code generation.
Short	Name for this evidence variable (computer friendly)
Comments	The name is not expected to be globally unique. The name should be a simple alphanumeric type name to ensure that it is machine-processing friendly.
Control	1..1 This element is affected by the following invariants: cnl-0
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	true
Summary	true
Requirements	Support human navigation and code generation.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
28. EvidenceVariable.title
Definition	A short, descriptive, user-friendly title for the evidence variable.
Short	Name for this evidence variable (human friendly)
Comments	This name does not need to be machine-processing friendly and may contain punctuation, white-space, etc.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
30. EvidenceVariable.shortTitle
Definition	The short title provides an alternate title for use in informal descriptive contexts where the full, formal title is not necessary.
Short	Title for use in informal contexts
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Requirements	Need to be able to reference the content by a short description, but still provide a longer, more formal title for the content.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
32. EvidenceVariable.status
Definition	The status of this evidence variable. Enables tracking the life-cycle of the content.
Short	draft \| active \| retired \| unknown
Comments	Allows filtering of evidence variables that are appropriate for use versus not. See guidance around (not) making local changes to elements here.
Control	1..1
Binding	The codes SHALL be taken from PublicationStatus (required to `http://hl7.org/fhir/ValueSet/publication-status\|5.0.0`) The lifecycle status of an artifact.
Type	code
Is Modifier	true because This is labeled as "Is Modifier" because applications should not use a retired {{title}} without due consideration
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
34. EvidenceVariable.experimental
Definition	A Boolean value to indicate that this resource is authored for testing purposes (or education/evaluation/marketing) and is not intended to be used for genuine usage.
Short	For testing purposes, not real usage
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	If absent, this resource is treated as though it is not experimental.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
36. EvidenceVariable.date
Definition	The date (and optionally time) when the evidence variable was last significantly changed. The date must change when the business version changes and it must change if the status code changes. In addition, it should change when the substantive content of the evidence variable changes.
Short	Date last changed
Comments	The date is often not tracked until the resource is published, but may be present on draft content. Note that this is not the same as the resource last-modified-date, since the resource may be a secondary representation of the evidence variable. Additional specific dates may be added as extensions or be found by consulting Provenances associated with past versions of the resource. See guidance around (not) making local changes to elements here.
Control	0..1
Type	dateTime
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Alternate Names	Revision Date
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
38. EvidenceVariable.publisher
Definition	The name of the organization or individual responsible for the release and ongoing maintenance of the evidence variable.
Short	Name of the publisher/steward (organization or individual)
Comments	Usually an organization but may be an individual. The publisher (or steward) of the evidence variable is the organization or individual primarily responsible for the maintenance and upkeep of the evidence variable. This is not necessarily the same individual or organization that developed and initially authored the content. The publisher is the primary point of contact for questions or issues with the evidence variable. This item SHOULD be populated unless the information is available from context.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Requirements	Helps establish the "authority/credibility" of the evidence variable. May also allow for contact.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
40. EvidenceVariable.contact
Definition	Contact details to assist a user in finding and communicating with the publisher.
Short	Contact details for the publisher
Comments	Extensions to ContactDetail include: contactReference, contactAddress, and contributionTime (see Clinical Reasoning Module). See guidance around (not) making local changes to elements here.
Control	0..*
Type	ContactDetail
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
42. EvidenceVariable.description
Definition	A free text natural language description of the evidence variable from a consumer's perspective.
Short	Natural language description of the evidence variable
Comments	This description can be used to capture details such as comments about misuse, instructions for clinical use and interpretation, literature references, examples from the paper world, etc. It is not a rendering of the evidence variable as conveyed in the 'text' field of the resource itself. This item SHOULD be populated unless the information is available from context (e.g. the language of the evidence variable is presumed to be the predominant language in the place the evidence variable was created).
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
44. EvidenceVariable.note
Definition	A human-readable string to clarify or explain concepts about the resource.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
46. EvidenceVariable.useContext
Definition	The content was developed with a focus and intent of supporting the contexts that are listed. These contexts may be general categories (gender, age, ...) or may be references to specific programs (insurance plans, studies, ...) and may be used to assist with indexing and searching for appropriate evidence variable instances.
Short	The context that the content is intended to support
Comments	When multiple useContexts are specified, there is no expectation that all or any of the contexts apply.
Control	0..*
Type	UsageContext
Is Modifier	false
Must Support	false
Summary	true
Requirements	Assist in searching for appropriate content.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
48. EvidenceVariable.purpose
Definition	Explanation of why this EvidenceVariable is needed and why it has been designed as it has.
Short	Why this EvidenceVariable is defined
Comments	This element does not describe the usage of the EvidenceVariable. Instead, it provides traceability of ''why'' the resource is either needed or ''why'' it is defined as it is. This may be used to point to source materials or specifications that drove the structure of this EvidenceVariable.
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
50. EvidenceVariable.copyright
Definition	A copyright statement relating to the resource and/or its contents. Copyright statements are generally legal restrictions on the use and publishing of the resource.
Short	Use and/or publishing restrictions
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
52. EvidenceVariable.copyrightLabel
Definition	A short string (<50 characters), suitable for inclusion in a page footer that identifies the copyright holder, effective period, and optionally whether rights are resctricted. (e.g. 'All rights reserved', 'Some rights reserved').
Short	Copyright holder and year(s)
Comments	The (c) symbol should NOT be included in this string. It will be added by software when rendering the notation. Full details about licensing, restrictions, warrantees, etc. goes in the more general 'copyright' element.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Defines the content expected to be rendered in all representations of the artifact.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
54. EvidenceVariable.approvalDate
Definition	The date on which the resource content was approved by the publisher. Approval happens once when the content is officially approved for usage. See guidance around (not) making local changes to elements here.
Short	When the resource was approved by publisher
Control	0..1
Type	date
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
56. EvidenceVariable.lastReviewDate
Definition	The date on which the resource content was last reviewed. Review happens periodically after approval but does not change the original approval date.
Short	When the resource was last reviewed by the publisher
Comments	If specified, this date follows the original approval date. See guidance around (not) making local changes to elements here.
Control	0..1
Type	date
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
58. EvidenceVariable.effectivePeriod
Definition	The period during which the resource content was or is planned to be in active use.
Short	When the resource is expected to be used
Comments	The effective period for an EvidenceVariable determines when the content is applicable for usage and is independent of publication and review dates. For example, a variable intended to be used for the year 2016 might be published in 2015. See guidance around (not) making local changes to elements here.
Control	0..1
Type	Period
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
60. EvidenceVariable.author
Definition	An individiual or organization primarily involved in the creation and maintenance of the content.
Short	Who authored the content
Comments	Extensions to ContactDetail include: contactReference, contactAddress, and contributionTime (see Clinical Reasoning Module).
Control	0..*
Type	ContactDetail
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
62. EvidenceVariable.editor
Definition	An individual or organization primarily responsible for internal coherence of the content.
Short	Who edited the content
Comments	Extensions to ContactDetail include: contactReference, contactAddress, and contributionTime (see Clinical Reasoning Module).
Control	0..*
Type	ContactDetail
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
64. EvidenceVariable.reviewer
Definition	An individual or organization asserted by the publisher to be primarily responsible for review of some aspect of the content.
Short	Who reviewed the content
Comments	Extensions to ContactDetail include: contactReference, contactAddress, and contributionTime (see Clinical Reasoning Module). See guidance around (not) making local changes to elements here.
Control	0..*
Type	ContactDetail
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
66. EvidenceVariable.endorser
Definition	An individual or organization asserted by the publisher to be responsible for officially endorsing the content for use in some setting.
Short	Who endorsed the content
Comments	Extensions to ContactDetail include: contactReference, contactAddress, and contributionTime (see Clinical Reasoning Module). See guidance around (not) making local changes to elements here.
Control	0..*
Type	ContactDetail
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
68. EvidenceVariable.relatedArtifact
Definition	Related artifacts such as additional documentation, justification, or bibliographic references.
Short	Additional documentation, citations, etc
Comments	Each related artifact is either an attachment, or a reference to another resource, but not both.
Control	0..*
Type	RelatedArtifact
Is Modifier	false
Must Support	false
Summary	false
Requirements	EvidenceVariables must be able to provide enough information for consumers of the content (and/or interventions or results produced by the content) to be able to determine and understand the justification for and evidence in support of the content.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
70. EvidenceVariable.actual
Definition	True if the actual variable measured, false if a conceptual representation of the intended variable.
Short	Actual or conceptual
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
72. EvidenceVariable.characteristic
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
74. EvidenceVariable.characteristic.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
76. EvidenceVariable.characteristic.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
78. EvidenceVariable.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
80. EvidenceVariable.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
82. EvidenceVariable.characteristic.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
84. EvidenceVariable.characteristic.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
86. EvidenceVariable.characteristic.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
88. EvidenceVariable.characteristic.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
90. EvidenceVariable.characteristic.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
92. EvidenceVariable.characteristic.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
94. EvidenceVariable.characteristic.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
96. EvidenceVariable.characteristic.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
98. EvidenceVariable.characteristic.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
100. EvidenceVariable.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
102. EvidenceVariable.characteristic.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
104. EvidenceVariable.characteristic.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
106. EvidenceVariable.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
108. EvidenceVariable.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
110. EvidenceVariable.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
112. EvidenceVariable.characteristic.definitionByTypeAndValue.type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
114. EvidenceVariable.characteristic.definitionByTypeAndValue.type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.type.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
116. EvidenceVariable.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
118. EvidenceVariable.characteristic.definitionByTypeAndValue.type.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
120. EvidenceVariable.characteristic.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
122. EvidenceVariable.characteristic.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
124. EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
126. EvidenceVariable.characteristic.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
128. EvidenceVariable.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
130. EvidenceVariable.characteristic.definitionByCombination.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
132. EvidenceVariable.characteristic.definitionByCombination.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
134. EvidenceVariable.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
136. EvidenceVariable.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombination (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
138. EvidenceVariable.characteristic.definitionByCombination.threshold
Definition	Provides the value of "n" when "at-least" or "at-most" codes are used.
Short	Provides the value of "n" when "at-least" or "at-most" codes are used
Control	0..1
Type	positiveInt
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
140. EvidenceVariable.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
142. EvidenceVariable.characteristic.definitionByCombination.characteristic.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
144. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
146. EvidenceVariable.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
148. EvidenceVariable.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
150. EvidenceVariable.characteristic.definitionByCombination.characteristic.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
152. EvidenceVariable.characteristic.definitionByCombination.characteristic.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
154. EvidenceVariable.characteristic.definitionByCombination.characteristic.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
156. EvidenceVariable.characteristic.definitionByCombination.characteristic.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
158. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
160. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
162. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
164. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
166. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
168. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
170. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
172. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
174. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
176. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
178. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
180. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
182. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
184. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
186. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
188. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
190. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
192. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
194. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
196. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
198. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
200. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
202. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
204. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombination (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
206. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.threshold
Definition	Provides the value of "n" when "at-least" or "at-most" codes are used.
Short	Provides the value of "n" when "at-least" or "at-most" codes are used
Control	0..1
Type	positiveInt
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
208. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
210. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
212. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
214. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
216. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
218. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
220. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
222. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
224. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
226. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
228. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
230. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
232. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
234. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
236. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
238. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
240. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
242. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
244. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
246. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
248. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
250. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
252. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
254. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
256. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
258. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
260. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
262. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
264. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
266. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
268. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
270. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
272. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombination (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
274. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.threshold
Definition	Provides the value of "n" when "at-least" or "at-most" codes are used.
Short	Provides the value of "n" when "at-least" or "at-most" codes are used
Control	0..1
Type	positiveInt
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
276. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
278. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
280. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
282. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
284. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
286. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
288. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
290. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
292. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
294. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
296. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
298. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
300. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
302. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
304. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
306. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
308. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
310. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
312. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
314. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
316. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
318. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
320. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
322. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
324. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
326. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
328. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
330. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
332. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
334. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
336. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
338. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
340. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombination (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
342. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.threshold
Definition	Provides the value of "n" when "at-least" or "at-most" codes are used.
Short	Provides the value of "n" when "at-least" or "at-most" codes are used
Control	0..1
Type	positiveInt
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
344. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic`. The slices areUnordered and Open, and can be differentiated using the following discriminators: pattern @ definitionByTypeAndValue.type
346. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
348. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
350. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
352. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
354. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
356. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
358. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
360. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
362. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
364. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
366. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
368. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
370. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
372. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
374. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
376. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
378. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
380. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
382. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
384. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
386. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
388. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
390. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.type.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
392. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
394. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
396. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
398. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
400. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
402. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
404. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
406. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
408. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.code
Definition	Used to specify if two or more characteristics are combined with OR or AND.
Short	all-of \| any-of \| at-least \| at-most \| statistical \| net-effect \| dataset
Control	1..1
Binding	The codes SHALL be taken from CharacteristicCombination (required to `http://hl7.org/fhir/ValueSet/characteristic-combination\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	If code is "at-least" or "at-most" then threshold SHALL be used. If code is neither "at-least" nor "at-most" then threshold SHALL NOT be used.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
410. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.threshold
Definition	Provides the value of "n" when "at-least" or "at-most" codes are used.
Short	Provides the value of "n" when "at-least" or "at-most" codes are used
Control	0..1
Type	positiveInt
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
412. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	1..*
Type	Seettp://hl7.org/fhir/StructureDefinition/EvidenceVariable#EvidenceVariable.characteristic
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
414. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
416. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
418. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
420. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
422. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
424. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
426. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
428. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
430. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
432. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
434. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
436. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
438. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
440. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
442. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
444. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
446. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
448. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
450. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
452. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
454. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
456. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
458. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
460. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
462. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
464. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
466. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
468. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
470. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
472. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
474. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
476. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
478. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
480. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
482. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
484. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
486. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
488. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
490. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
492. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
494. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
502. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
504. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
506. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
508. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
510. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
512. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
514. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
516. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
518. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
520. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
522. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
524. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
526. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
528. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
530. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
532. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
534. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
536. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
538. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
540. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
542. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
544. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
546. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
548. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
550. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
552. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
554. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
556. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
558. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
560. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
562. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
564. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
566. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
568. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
570. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
572. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
574. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
576. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
578. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
580. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
582. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
590. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
592. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
594. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
596. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
598. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
600. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
602. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
604. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
606. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
608. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
610. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
612. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
614. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
616. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
618. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
620. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
622. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
624. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
626. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
628. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
630. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
632. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
634. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
636. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
638. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
640. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
642. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
644. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
646. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
648. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
650. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
652. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
654. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
656. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
658. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
660. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
662. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
664. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
666. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
668. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
670. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
678. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
680. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
682. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
684. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
686. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
688. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
690. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
692. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
694. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
696. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
698. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
700. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
702. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
704. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
706. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
708. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
710. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
712. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
714. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
716. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
718. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
720. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
722. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
724. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
726. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
728. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
730. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
732. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
734. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
736. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
738. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
740. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
742. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
744. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
746. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
748. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
750. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
752. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
754. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
756. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
758. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
766. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
768. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
770. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
772. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
774. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
776. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
778. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
780. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
782. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
784. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
786. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
788. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
790. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
792. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
794. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
796. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
798. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
800. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
802. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
804. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
806. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
808. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
810. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
812. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
814. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
816. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
818. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
820. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
822. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
824. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
826. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
828. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
830. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
832. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
834. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
836. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
838. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
840. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
842. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
844. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
846. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
854. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
856. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
858. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
860. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
862. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
864. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
866. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
868. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
870. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
872. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
874. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
876. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
878. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
880. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
882. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
884. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
886. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
888. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
890. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
892. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
894. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
896. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
898. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
900. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
902. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
904. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
906. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
908. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
910. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
912. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
914. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
916. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
918. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
920. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
922. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
924. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
932. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
934. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
936. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
938. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
940. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
942. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
944. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
946. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
948. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
950. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
952. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
954. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
956. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
958. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
960. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
962. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
964. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
966. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
968. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
970. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
972. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
974. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
976. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
978. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
980. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
982. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
984. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
986. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
988. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
990. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
992. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
994. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
996. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
998. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1000. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1002. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1004. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1006. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1008. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1010. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1012. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1020. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1022. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1024. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1026. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1028. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1030. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1032. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1034. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1036. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1038. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1040. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1042. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1044. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1046. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1048. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1050. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1052. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1054. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1056. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1058. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1060. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1062. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1064. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1066. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1068. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1070. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1072. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1074. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1076. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1078. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1080. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1082. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1084. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1086. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1088. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1090. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1098. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1100. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1102. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1104. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1106. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1108. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1110. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1112. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1114. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1116. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1118. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1120. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1122. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1124. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1126. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1128. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1130. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1132. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1134. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1136. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1138. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1140. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1142. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1144. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1146. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1148. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1150. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1152. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1154. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1156. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1158. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1160. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1162. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1164. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1166. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1168. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1170. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1172. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1174. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1176. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1178. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1180. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1188. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1190. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1192. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1194. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1196. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1198. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1200. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1202. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1204. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1206. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1208. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1210. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1212. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1214. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1216. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1218. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1220. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1222. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1224. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1226. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1228. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1230. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1232. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1234. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1236. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1238. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1240. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1242. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1244. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1246. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1248. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1250. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1252. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1254. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1256. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1258. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1260. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1262. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1264. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1266. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1268. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1270. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1272. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1274. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1276. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1278. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1280. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1282. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1284. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1286. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1288. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1290. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1298. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1300. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1302. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1304. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1306. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1308. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1310. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1312. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1314. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1316. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1318. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1320. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1322. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1324. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1326. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1328. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1330. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1332. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1334. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1336. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1338. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1340. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1342. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1344. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1346. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1348. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1350. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1352. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1354. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1356. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1358. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1360. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1362. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1364. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1366. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1368. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1370. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1372. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1374. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1376. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1378. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1386. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1388. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1390. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1392. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1394. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1396. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1398. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1400. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1402. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1404. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1406. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1408. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1410. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1412. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1414. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1416. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1418. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1420. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1422. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1424. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1426. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1428. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1430. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1432. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1434. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1436. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1438. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1440. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1442. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1444. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1446. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1448. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1450. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1452. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1454. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1456. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1458. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1460. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1462. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1464. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1466. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1474. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1476. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1478. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1480. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1482. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1484. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1486. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1488. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1490. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1492. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1494. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1496. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1498. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1500. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1502. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1504. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1506. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1508. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1510. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1512. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1514. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1516. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1518. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1520. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1522. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1524. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1526. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1528. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1530. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1532. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1534. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1536. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1538. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1540. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1542. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1544. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1546. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1548. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1550. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1552. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1554. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1562. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1564. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1566. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1568. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1570. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1572. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1574. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1576. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1578. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1580. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1582. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1584. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1586. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1588. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1590. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1592. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1594. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1596. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1598. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1600. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1602. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1604. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1606. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1608. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1610. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1612. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1614. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1616. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1618. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1620. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1622. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1624. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1626. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1628. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1630. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1632. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1634. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1636. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1638. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1640. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1642. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1650. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1652. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1654. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1656. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1658. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1660. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1662. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1664. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1666. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1668. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1670. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1672. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1674. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1676. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1678. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1680. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1682. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1684. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1686. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1688. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1690. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1692. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1694. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1696. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1698. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1700. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1702. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1704. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1706. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1708. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1710. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1712. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1714. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1716. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1718. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1720. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1728. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1730. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1732. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1734. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1736. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1738. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1740. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1742. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1744. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1746. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1748. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1750. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1752. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1754. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1756. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1758. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1760. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1762. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1764. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1766. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1768. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1770. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1772. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1774. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1776. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1778. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1780. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1782. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1784. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1786. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1788. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1790. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1792. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1794. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1796. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1798. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1800. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1802. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1804. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1806. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1808. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1816. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1818. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1820. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1822. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1824. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1826. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1828. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1830. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1832. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1834. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1836. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1838. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1840. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1842. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1844. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1846. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1848. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1850. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1852. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1854. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1856. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1858. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1860. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1862. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1864. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1866. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1868. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1870. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1872. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1874. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1876. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1878. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1880. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1882. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1884. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1886. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1894. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1896. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1898. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1900. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1902. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1904. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1906. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1908. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1910. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1912. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1914. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1916. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1918. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1920. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1922. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1924. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1926. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1928. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1930. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1932. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1934. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1936. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1938. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1940. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1942. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1944. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1946. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1948. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1950. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1952. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1954. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1956. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1958. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1960. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1962. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
1964. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1966. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1968. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
1970. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1972. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1974. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1976. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1984. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1986. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1988. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1990. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
1992. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1994. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
1996. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
1998. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2000. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2002. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2004. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2006. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2008. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2010. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2012. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2014. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2016. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2018. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2020. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2022. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2024. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2026. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2028. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2030. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2032. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2034. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2036. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2038. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2040. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2042. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2044. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2046. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2048. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2050. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2052. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2054. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2056. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2058. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2060. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2062. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2064. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2066. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2068. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2070. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2072. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2074. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2076. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2078. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2080. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2082. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2084. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2086. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2094. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2096. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2098. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2100. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2102. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2104. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2106. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2108. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2110. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2112. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2114. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2116. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2118. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2120. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2122. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2124. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2126. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2128. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2130. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2132. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2134. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2136. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2138. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2140. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2142. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2144. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2146. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2148. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2150. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2152. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2154. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2156. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2158. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2160. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2162. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2164. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2166. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2168. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2170. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2172. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2174. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2182. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2184. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2186. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2188. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2190. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2192. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2194. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2196. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2198. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2200. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2202. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2204. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2206. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2208. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2210. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2212. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2214. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2216. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2218. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2220. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2222. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2224. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2226. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2228. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2230. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2232. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2234. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2236. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2238. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2240. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2242. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2244. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2246. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2248. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2250. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2252. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2254. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2256. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2258. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2260. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2262. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2270. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2272. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2274. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2276. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2278. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2280. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2282. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2284. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2286. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2288. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2290. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2292. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2294. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2296. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2298. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2300. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2302. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2304. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2306. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2308. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2310. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2312. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2314. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2316. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2318. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2320. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2322. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2324. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2326. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2328. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2330. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2332. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2334. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2336. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2338. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2340. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2342. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2344. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2346. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2348. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2350. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2358. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2360. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2362. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2364. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2366. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2368. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2370. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2372. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2374. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2376. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2378. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2380. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2382. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2384. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2386. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2388. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2390. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2392. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2394. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2396. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2398. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2400. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2402. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2404. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2406. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2408. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2410. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2412. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2414. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2416. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2418. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2420. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2422. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2424. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2426. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2428. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2430. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2432. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2434. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2436. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2438. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2446. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2448. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2450. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2452. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2454. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2456. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2458. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2460. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2462. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2464. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2466. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2468. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2470. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2472. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2474. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2476. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2478. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2480. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2482. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2484. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2486. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2488. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2490. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2492. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2494. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2496. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2498. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2500. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2502. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2504. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2506. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2508. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2510. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2512. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2514. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2516. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2524. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2526. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2528. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2530. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2532. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2534. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2536. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2538. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2540. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2542. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2544. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2546. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2548. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2550. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2552. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2554. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2556. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2558. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2560. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2562. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2564. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2566. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2568. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2570. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2572. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2574. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2576. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2578. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2580. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2582. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2584. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2586. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2588. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2590. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2592. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2594. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2596. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2598. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2600. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2602. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2604. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2612. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2614. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2616. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2618. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2620. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2622. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2624. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2626. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2628. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2630. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2632. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:device.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2634. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2636. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2638. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2640. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2642. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2644. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2646. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2648. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2650. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2652. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2654. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2656. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2658. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2660. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2662. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2664. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2666. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2668. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2670. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2672. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2674. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2676. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2678. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2680. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2682. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2690. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2692. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2694. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2696. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2698. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2700. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2702. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2704. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2706. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2708. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2710. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2712. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2714. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2716. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2718. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2720. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2722. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2724. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2726. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2728. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2730. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2732. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2734. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2736. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2738. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2740. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2742. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2744. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2746. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2748. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2750. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2752. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2754. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2756. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2758. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2760. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2762. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2764. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2766. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2768. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2770. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2772. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2780. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2782. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2784. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2786. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2788. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2790. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2792. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2794. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2796. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2798. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2800. EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2802. EvidenceVariable.characteristic.definitionByCombination.characteristic.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2804. EvidenceVariable.characteristic.definitionByCombination.characteristic.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2806. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2808. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2810. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2812. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2814. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2816. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2818. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2820. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2822. EvidenceVariable.characteristic.definitionByCombination.characteristic.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2824. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition
Slice Name	condition
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
2826. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2828. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2830. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2832. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2834. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2836. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2838. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2840. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2842. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2844. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2846. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2848. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2850. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2852. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2854. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2856. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2858. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2860. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2862. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2864. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2866. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2868. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2870. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2872. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2874. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2876. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2878. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2880. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2882. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2890. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2892. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2894. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2896. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2898. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2900. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2902. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2904. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2906. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2908. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2910. EvidenceVariable.characteristic.definitionByCombination.characteristic:condition.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2912. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
2914. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2916. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2918. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2920. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2922. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2924. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2926. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2928. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2930. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2932. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2934. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2936. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2938. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2940. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2942. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2944. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2946. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2948. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2950. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2952. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2954. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2956. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
2958. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2960. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2962. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
2964. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2966. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2968. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2970. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2978. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2980. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2982. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2984. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
2986. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2988. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
2990. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2992. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2994. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2996. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
2998. EvidenceVariable.characteristic.definitionByCombination.characteristic:allergy.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3000. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3002. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3004. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3006. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3008. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3010. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3012. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3014. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3016. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3018. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3020. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3022. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3024. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3026. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3028. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3030. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3032. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3034. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3036. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3038. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3040. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3042. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3044. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3046. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3048. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3050. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3052. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3054. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3056. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3058. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3066. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3068. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3070. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3072. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3074. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3076. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3078. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3080. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3082. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3084. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3086. EvidenceVariable.characteristic.definitionByCombination.characteristic:radiologyFinding.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3088. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3090. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3092. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3094. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3096. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3098. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3100. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3102. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3104. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3106. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3108. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3110. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3112. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3114. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3116. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3118. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3120. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3122. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3124. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3126. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3128. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3130. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3132. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3134. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3136. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3138. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3140. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3142. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3144. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3146. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3154. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3156. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3158. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3160. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3162. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3164. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3166. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3168. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3170. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3172. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3174. EvidenceVariable.characteristic.definitionByCombination.characteristic:episodeOfCare.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3176. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3178. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3180. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3182. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3184. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3186. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3188. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3190. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3192. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3194. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3196. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3198. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3200. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3202. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3204. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3206. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3208. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3210. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3212. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3214. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3216. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3218. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3220. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3222. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3224. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3226. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3228. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3230. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3232. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3234. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3242. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3244. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3246. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3248. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3250. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3252. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3254. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3256. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3258. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3260. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3262. EvidenceVariable.characteristic.definitionByCombination.characteristic:procedure.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3264. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3266. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3268. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3270. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3272. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3274. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3276. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3278. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3280. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3282. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3284. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3286. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3288. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3290. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3292. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3294. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3296. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3298. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3300. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3302. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3304. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3306. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3308. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3310. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3312. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3320. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3322. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3324. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3326. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3328. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3330. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3332. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3334. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3336. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3338. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3340. EvidenceVariable.characteristic.definitionByCombination.characteristic:assessmentScale.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3342. EvidenceVariable.characteristic.definitionByCombination.characteristic:device
Slice Name	device
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3344. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3346. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3348. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3350. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3352. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3354. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3356. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3358. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3360. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3362. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3364. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3366. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3368. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3370. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3372. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3374. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3376. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3378. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3380. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3382. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3384. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3386. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3388. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3390. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3392. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3394. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3396. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3398. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3400. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3408. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3410. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3412. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3414. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3416. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3418. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3420. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3422. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3424. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3426. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3428. EvidenceVariable.characteristic.definitionByCombination.characteristic:device.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3430. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation
Slice Name	observation
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3432. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3434. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3436. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3438. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3440. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3442. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3444. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3446. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3448. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3450. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3452. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3454. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3456. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3458. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3460. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3462. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3464. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3466. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3468. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3470. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3472. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3474. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3476. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3478. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3486. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3488. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3490. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3492. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3494. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3496. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3498. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3500. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3502. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3504. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3506. EvidenceVariable.characteristic.definitionByCombination.characteristic:observation.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3508. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the characteristic.
Short	A defining factor of the characteristic
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3510. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3512. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3514. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3516. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3518. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3520. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3522. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3524. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3526. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3528. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3530. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3532. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3534. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3536. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3538. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3540. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3542. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3544. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3546. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3548. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3550. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3552. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3554. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3556. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3558. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3560. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByCombination.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3562. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3564. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3566. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3568. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3576. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3578. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3580. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3582. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3584. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3586. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3588. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3590. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3592. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3594. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3596. EvidenceVariable.characteristic.definitionByCombination.characteristic:drugAdministration.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3598. EvidenceVariable.characteristic.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3600. EvidenceVariable.characteristic.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3602. EvidenceVariable.characteristic.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3604. EvidenceVariable.characteristic.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3606. EvidenceVariable.characteristic.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3608. EvidenceVariable.characteristic.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3610. EvidenceVariable.characteristic.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3612. EvidenceVariable.characteristic.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3614. EvidenceVariable.characteristic.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3616. EvidenceVariable.characteristic.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3618. EvidenceVariable.characteristic.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3620. EvidenceVariable.characteristic:condition
Slice Name	condition
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3622. EvidenceVariable.characteristic:condition.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3624. EvidenceVariable.characteristic:condition.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3626. EvidenceVariable.characteristic:condition.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3628. EvidenceVariable.characteristic:condition.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3630. EvidenceVariable.characteristic:condition.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3632. EvidenceVariable.characteristic:condition.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3634. EvidenceVariable.characteristic:condition.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3636. EvidenceVariable.characteristic:condition.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3638. EvidenceVariable.characteristic:condition.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3640. EvidenceVariable.characteristic:condition.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3642. EvidenceVariable.characteristic:condition.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3644. EvidenceVariable.characteristic:condition.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3646. EvidenceVariable.characteristic:condition.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3648. EvidenceVariable.characteristic:condition.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3650. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3652. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3654. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3656. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3658. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "404684003", "display" : "Clinical finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3660. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3662. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3664. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3666. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from SNOMEDCTClinicalFindings (extensible to `http://hl7.org/fhir/ValueSet/clinical-findings`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3668. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3670. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3672. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3674. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3676. EvidenceVariable.characteristic:condition.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3678. EvidenceVariable.characteristic:condition.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3686. EvidenceVariable.characteristic:condition.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3688. EvidenceVariable.characteristic:condition.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3690. EvidenceVariable.characteristic:condition.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3692. EvidenceVariable.characteristic:condition.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3694. EvidenceVariable.characteristic:condition.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3696. EvidenceVariable.characteristic:condition.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3698. EvidenceVariable.characteristic:condition.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3700. EvidenceVariable.characteristic:condition.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3702. EvidenceVariable.characteristic:condition.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3704. EvidenceVariable.characteristic:condition.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3706. EvidenceVariable.characteristic:condition.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3708. EvidenceVariable.characteristic:allergy
Slice Name	allergy
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3710. EvidenceVariable.characteristic:allergy.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3712. EvidenceVariable.characteristic:allergy.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3714. EvidenceVariable.characteristic:allergy.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3716. EvidenceVariable.characteristic:allergy.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3718. EvidenceVariable.characteristic:allergy.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3720. EvidenceVariable.characteristic:allergy.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3722. EvidenceVariable.characteristic:allergy.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3724. EvidenceVariable.characteristic:allergy.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3726. EvidenceVariable.characteristic:allergy.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3728. EvidenceVariable.characteristic:allergy.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3730. EvidenceVariable.characteristic:allergy.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3732. EvidenceVariable.characteristic:allergy.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3734. EvidenceVariable.characteristic:allergy.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3736. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3738. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3740. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3742. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3744. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3746. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "609328004", "display" : "Allergic disposition (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3748. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3750. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3752. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3754. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Allergic Disposition SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-allergic-disposition-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3756. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3758. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3760. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3762. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3764. EvidenceVariable.characteristic:allergy.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3766. EvidenceVariable.characteristic:allergy.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3774. EvidenceVariable.characteristic:allergy.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3776. EvidenceVariable.characteristic:allergy.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3778. EvidenceVariable.characteristic:allergy.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3780. EvidenceVariable.characteristic:allergy.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3782. EvidenceVariable.characteristic:allergy.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3784. EvidenceVariable.characteristic:allergy.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3786. EvidenceVariable.characteristic:allergy.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3788. EvidenceVariable.characteristic:allergy.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3790. EvidenceVariable.characteristic:allergy.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3792. EvidenceVariable.characteristic:allergy.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3794. EvidenceVariable.characteristic:allergy.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3796. EvidenceVariable.characteristic:radiologyFinding
Slice Name	radiologyFinding
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3798. EvidenceVariable.characteristic:radiologyFinding.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3800. EvidenceVariable.characteristic:radiologyFinding.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3802. EvidenceVariable.characteristic:radiologyFinding.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3804. EvidenceVariable.characteristic:radiologyFinding.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3806. EvidenceVariable.characteristic:radiologyFinding.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3808. EvidenceVariable.characteristic:radiologyFinding.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3810. EvidenceVariable.characteristic:radiologyFinding.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3812. EvidenceVariable.characteristic:radiologyFinding.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3814. EvidenceVariable.characteristic:radiologyFinding.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3816. EvidenceVariable.characteristic:radiologyFinding.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3818. EvidenceVariable.characteristic:radiologyFinding.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3820. EvidenceVariable.characteristic:radiologyFinding.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3822. EvidenceVariable.characteristic:radiologyFinding.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3824. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3826. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3828. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3830. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3832. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3834. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "118247008", "display" : "Radiologic finding (finding)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3836. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3838. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3840. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3842. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Radiologic Finding SCT (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-radiologic-finding-sct`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3844. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3846. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3848. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3850. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3852. EvidenceVariable.characteristic:radiologyFinding.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3854. EvidenceVariable.characteristic:radiologyFinding.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3862. EvidenceVariable.characteristic:radiologyFinding.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3864. EvidenceVariable.characteristic:radiologyFinding.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3866. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3868. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3870. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3872. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3874. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3876. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3878. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3880. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3882. EvidenceVariable.characteristic:radiologyFinding.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3884. EvidenceVariable.characteristic:episodeOfCare
Slice Name	episodeOfCare
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3886. EvidenceVariable.characteristic:episodeOfCare.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3888. EvidenceVariable.characteristic:episodeOfCare.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3890. EvidenceVariable.characteristic:episodeOfCare.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3892. EvidenceVariable.characteristic:episodeOfCare.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3894. EvidenceVariable.characteristic:episodeOfCare.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3896. EvidenceVariable.characteristic:episodeOfCare.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3898. EvidenceVariable.characteristic:episodeOfCare.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3900. EvidenceVariable.characteristic:episodeOfCare.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3902. EvidenceVariable.characteristic:episodeOfCare.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3904. EvidenceVariable.characteristic:episodeOfCare.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3906. EvidenceVariable.characteristic:episodeOfCare.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3908. EvidenceVariable.characteristic:episodeOfCare.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3910. EvidenceVariable.characteristic:episodeOfCare.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3912. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3914. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3916. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3918. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3920. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3922. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://loinc.org", "code" : "78030-4", "display" : "Episode of care Type" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3924. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3926. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3928. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
3930. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Episode Of Care Type (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-episode-of-care-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3932. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3934. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3936. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3938. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3940. EvidenceVariable.characteristic:episodeOfCare.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3942. EvidenceVariable.characteristic:episodeOfCare.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3950. EvidenceVariable.characteristic:episodeOfCare.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3952. EvidenceVariable.characteristic:episodeOfCare.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3954. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3956. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3958. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3960. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3962. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3964. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3966. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3968. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3970. EvidenceVariable.characteristic:episodeOfCare.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3972. EvidenceVariable.characteristic:procedure
Slice Name	procedure
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
3974. EvidenceVariable.characteristic:procedure.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
3976. EvidenceVariable.characteristic:procedure.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
3978. EvidenceVariable.characteristic:procedure.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3980. EvidenceVariable.characteristic:procedure.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
3982. EvidenceVariable.characteristic:procedure.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3984. EvidenceVariable.characteristic:procedure.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3986. EvidenceVariable.characteristic:procedure.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3988. EvidenceVariable.characteristic:procedure.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3990. EvidenceVariable.characteristic:procedure.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3992. EvidenceVariable.characteristic:procedure.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3994. EvidenceVariable.characteristic:procedure.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3996. EvidenceVariable.characteristic:procedure.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
3998. EvidenceVariable.characteristic:procedure.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4000. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4002. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4004. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4006. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4008. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4010. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "71388002", "display" : "Procedure (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4012. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4014. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4016. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
4018. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from ProcedureCodesSNOMEDCT (extensible to `http://hl7.org/fhir/ValueSet/procedure-code`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4020. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4022. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4024. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4026. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4028. EvidenceVariable.characteristic:procedure.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4030. EvidenceVariable.characteristic:procedure.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4038. EvidenceVariable.characteristic:procedure.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4040. EvidenceVariable.characteristic:procedure.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4042. EvidenceVariable.characteristic:procedure.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4044. EvidenceVariable.characteristic:procedure.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4046. EvidenceVariable.characteristic:procedure.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4048. EvidenceVariable.characteristic:procedure.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4050. EvidenceVariable.characteristic:procedure.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4052. EvidenceVariable.characteristic:procedure.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4054. EvidenceVariable.characteristic:procedure.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4056. EvidenceVariable.characteristic:procedure.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4058. EvidenceVariable.characteristic:procedure.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4060. EvidenceVariable.characteristic:assessmentScale
Slice Name	assessmentScale
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
4062. EvidenceVariable.characteristic:assessmentScale.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4064. EvidenceVariable.characteristic:assessmentScale.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4066. EvidenceVariable.characteristic:assessmentScale.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4068. EvidenceVariable.characteristic:assessmentScale.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4070. EvidenceVariable.characteristic:assessmentScale.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4072. EvidenceVariable.characteristic:assessmentScale.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4074. EvidenceVariable.characteristic:assessmentScale.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4076. EvidenceVariable.characteristic:assessmentScale.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4078. EvidenceVariable.characteristic:assessmentScale.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4080. EvidenceVariable.characteristic:assessmentScale.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4082. EvidenceVariable.characteristic:assessmentScale.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4084. EvidenceVariable.characteristic:assessmentScale.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4086. EvidenceVariable.characteristic:assessmentScale.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4088. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4090. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4092. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4094. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4096. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4098. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Assessment Scales (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-assessment-scales`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4100. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4102. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4104. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4106. EvidenceVariable.characteristic:assessmentScale.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4108. EvidenceVariable.characteristic:assessmentScale.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4116. EvidenceVariable.characteristic:assessmentScale.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4118. EvidenceVariable.characteristic:assessmentScale.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4120. EvidenceVariable.characteristic:assessmentScale.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4122. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4124. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4126. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4128. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4130. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4132. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4134. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4136. EvidenceVariable.characteristic:assessmentScale.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4138. EvidenceVariable.characteristic:device
Slice Name	device
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
4140. EvidenceVariable.characteristic:device.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4142. EvidenceVariable.characteristic:device.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4144. EvidenceVariable.characteristic:device.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4146. EvidenceVariable.characteristic:device.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4148. EvidenceVariable.characteristic:device.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4150. EvidenceVariable.characteristic:device.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4152. EvidenceVariable.characteristic:device.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4154. EvidenceVariable.characteristic:device.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4156. EvidenceVariable.characteristic:device.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4158. EvidenceVariable.characteristic:device.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4160. EvidenceVariable.characteristic:device.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4162. EvidenceVariable.characteristic:device.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4164. EvidenceVariable.characteristic:device.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4166. EvidenceVariable.characteristic:device.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4168. EvidenceVariable.characteristic:device.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4170. EvidenceVariable.characteristic:device.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4172. EvidenceVariable.characteristic:device.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4174. EvidenceVariable.characteristic:device.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4176. EvidenceVariable.characteristic:device.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "49062001", "display" : "Device (physical object)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4178. EvidenceVariable.characteristic:device.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4180. EvidenceVariable.characteristic:device.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4182. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
4184. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from DeviceType (extensible to `http://hl7.org/fhir/ValueSet/device-type`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4186. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4188. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4190. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4192. EvidenceVariable.characteristic:device.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4194. EvidenceVariable.characteristic:device.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4196. EvidenceVariable.characteristic:device.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4204. EvidenceVariable.characteristic:device.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4206. EvidenceVariable.characteristic:device.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4208. EvidenceVariable.characteristic:device.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4210. EvidenceVariable.characteristic:device.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4212. EvidenceVariable.characteristic:device.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4214. EvidenceVariable.characteristic:device.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4216. EvidenceVariable.characteristic:device.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4218. EvidenceVariable.characteristic:device.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4220. EvidenceVariable.characteristic:device.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4222. EvidenceVariable.characteristic:device.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4224. EvidenceVariable.characteristic:device.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4226. EvidenceVariable.characteristic:observation
Slice Name	observation
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
4228. EvidenceVariable.characteristic:observation.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4230. EvidenceVariable.characteristic:observation.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4232. EvidenceVariable.characteristic:observation.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4234. EvidenceVariable.characteristic:observation.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4236. EvidenceVariable.characteristic:observation.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4238. EvidenceVariable.characteristic:observation.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4240. EvidenceVariable.characteristic:observation.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4242. EvidenceVariable.characteristic:observation.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4244. EvidenceVariable.characteristic:observation.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4246. EvidenceVariable.characteristic:observation.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4248. EvidenceVariable.characteristic:observation.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4250. EvidenceVariable.characteristic:observation.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4252. EvidenceVariable.characteristic:observation.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4254. EvidenceVariable.characteristic:observation.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4256. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4258. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4260. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4262. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4264. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	The codes SHALL be taken from Observations (required to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-observations`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4266. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4268. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4270. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4272. EvidenceVariable.characteristic:observation.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4274. EvidenceVariable.characteristic:observation.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4282. EvidenceVariable.characteristic:observation.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4284. EvidenceVariable.characteristic:observation.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4286. EvidenceVariable.characteristic:observation.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4288. EvidenceVariable.characteristic:observation.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4290. EvidenceVariable.characteristic:observation.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4292. EvidenceVariable.characteristic:observation.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4294. EvidenceVariable.characteristic:observation.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4296. EvidenceVariable.characteristic:observation.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4298. EvidenceVariable.characteristic:observation.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4300. EvidenceVariable.characteristic:observation.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4302. EvidenceVariable.characteristic:observation.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4304. EvidenceVariable.characteristic:drugAdministration
Slice Name	drugAdministration
Definition	A defining factor of the EvidenceVariable. Multiple characteristics are applied with "and" semantics.
Short	A defining factor of the EvidenceVariable
Comments	Characteristics can be defined flexibly to accommodate different use cases for membership criteria, ranging from simple codes, all the way to using an expression language to express the criteria.
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	true
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) evv-1: In a characteristic, at most one of these six elements shall be used: definitionReference or definitionCanonical or definitionCodeableConcept or definitionId or definitionByTypeAndValue or definitionByCombination (`(definitionReference.count() + definitionCanonical.count() + definitionCodeableConcept.count() + definitionId.count() + definitionByTypeAndValue.count() + definitionByCombination.count()) < 2`) evidence-variable-unique-definition: For each characteristic, one and only one type of definition must exist (`( definitionReference.exists().toInteger() + definitionCanonical.exists().toInteger() + definitionCodeableConcept.exists().toInteger() + definitionExpression.exists().toInteger() + definitionId.exists().toInteger() + definitionByTypeAndValue.exists().toInteger() + definitionByCombination.exists().toInteger() ) = 1`)
4306. EvidenceVariable.characteristic:drugAdministration.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4308. EvidenceVariable.characteristic:drugAdministration.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4310. EvidenceVariable.characteristic:drugAdministration.extension:relativeTime
Slice Name	relativeTime
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	Extension(RelativeTime) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4312. EvidenceVariable.characteristic:drugAdministration.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4314. EvidenceVariable.characteristic:drugAdministration.linkId
Definition	Label used for when a characteristic refers to another characteristic.
Short	Label for internal linking
Control	0..1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4316. EvidenceVariable.characteristic:drugAdministration.description
Definition	A short, natural language description of the characteristic that could be used to communicate the criteria to an end-user.
Short	Natural language description of the characteristic
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Requirements	Need to be able to describe characteristics in natural language so that end users can understand the criteria.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4318. EvidenceVariable.characteristic:drugAdministration.note
Definition	A human-readable string to clarify or explain concepts about the characteristic.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4320. EvidenceVariable.characteristic:drugAdministration.exclude
Definition	When true, this characteristic is an exclusion criterion. In other words, not matching this characteristic definition is equivalent to meeting this criterion.
Short	Whether the characteristic is an inclusion criterion or exclusion criterion
Control	0..1
Type	boolean
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Meaning if Missing	False
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4322. EvidenceVariable.characteristic:drugAdministration.definitionReference
Definition	Defines the characteristic using a Reference.
Short	Defines the characteristic (without using type and value) by a Reference
Control	0..1 This element is affected by the following invariants: evv-1
Type	Reference(EvidenceVariable, Group, Evidence)
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4324. EvidenceVariable.characteristic:drugAdministration.definitionCanonical
Definition	Defines the characteristic using Canonical.
Short	Defines the characteristic (without using type and value) by a Canonical
Control	0..1 This element is affected by the following invariants: evv-1
Type	canonical(EvidenceVariable, Evidence)
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4326. EvidenceVariable.characteristic:drugAdministration.definitionCodeableConcept
Definition	Defines the characteristic using CodeableConcept.
Short	Defines the characteristic (without using type and value) by a CodeableConcept
Control	0..1 This element is affected by the following invariants: evv-1
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4328. EvidenceVariable.characteristic:drugAdministration.definitionExpression
Definition	Defines the characteristic using Expression.
Short	Defines the characteristic (without using type and value) by an expression
Comments	When another element provides a definition of the characteristic, the definitionExpression content SHALL match the definition (only adding technical concepts necessary for implementation) without changing the meaning.
Control	0..1
Type	Expression
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4330. EvidenceVariable.characteristic:drugAdministration.definitionId
Definition	Defines the characteristic using id.
Short	Defines the characteristic (without using type and value) by an id
Control	0..1 This element is affected by the following invariants: evv-1
Type	id
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4332. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue
Definition	Defines the characteristic using both a type and value[x] elements.
Short	Defines the characteristic using type and value
Control	1..1 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4334. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4336. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension
Definition	An Extension
Short	Extension
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4338. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:attribute
Slice Name	attribute
Definition	Define an attribute of a characteristic.
Short	Characteristic Attribute
Control	0..*
Type	Extension(Characteristic Attribute) (Complex Extension)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4340. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.extension:dosage
Slice Name	dosage
Definition	Adds Dosage type to characteristic
Short	Characteristic Dosage
Control	0..*
Type	Extension(Characteristic Dosage) (Extension Type: Dosage)
Is Modifier	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4342. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4344. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.type
Definition	Used to express the type of characteristic.
Short	Expresses the type of characteristic
Control	1..1
Binding	For example codes, see UsageContextType (example to `http://terminology.hl7.org/ValueSet/usage-context-type`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	true
Pattern Value	`{ "coding" : [{ "system" : "http://snomed.info/sct", "code" : "18629005", "display" : "Administration of drug or medicament (procedure)" }] }`
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4346. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.method
Definition	Method for how the characteristic value was determined.
Short	Method for how the characteristic value was determined
Control	0..*
Binding	For example codes, see DefinitionMethod (example to `http://hl7.org/fhir/ValueSet/definition-method`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4348. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.device
Definition	Device used for determining characteristic.
Short	Device used for determining characteristic
Control	0..1
Type	Reference(Device, DeviceMetric)
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4350. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	1..1
Type	Choice of: CodeableConcept, boolean, Quantity, Range, Reference, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x]`. The slices areUnordered and Open, and can be differentiated using the following discriminators: type @ $this
4352. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept
Slice Name	valueCodeableConcept
Definition	Defines the characteristic when paired with characteristic.type.
Short	Defines the characteristic when coupled with characteristic.type
Control	0..1
Binding	Unless not suitable, these codes SHALL be taken from Drugs (extensible to `https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/ValueSet/vs-drugs`)
Type	CodeableConcept
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	true
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4354. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	id
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4356. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
Slicing	This element introduces a set of slices on `EvidenceVariable.characteristic.definitionByTypeAndValue.value[x].extension`. The slices areUnordered and Open, and can be differentiated using the following discriminators: value @ url
4358. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.coding
Definition	A reference to a code defined by a terminology system.
Short	Code defined by a terminology system
Comments	Codes may be defined very casually in enumerations, or code lists, up to very formal definitions such as SNOMED CT - see the HL7 v3 Core Principles for more information. Ordering of codings is undefined and SHALL NOT be used to infer meaning. Generally, at most only one of the coding values will be labeled as UserSelected = true.
Control	1..1
Type	Coding
Is Modifier	false
Must Support	true
Summary	true
Requirements	Allows for alternative encodings within a code system, and translations to other code systems.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4360. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.value[x]:valueCodeableConcept.text
Definition	A human language representation of the concept as seen/selected/uttered by the user who entered the data and/or which represents the intended meaning of the user.
Short	Plain text representation of the concept
Comments	Very often the text is the same as a displayName of one of the codings.
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Summary	true
Requirements	The codes from the terminologies do not always capture the correct meaning with all the nuances of the human using them, or sometimes there is no appropriate code at all. In these cases, the text is used to capture the full meaning of the source.
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4362. EvidenceVariable.characteristic:drugAdministration.definitionByTypeAndValue.offset
Definition	Defines the reference point for comparison when valueQuantity or valueRange is not compared to zero.
Short	Reference point for valueQuantity or valueRange
Control	0..1
Binding	For example codes, see CharacteristicOffset (example to `http://hl7.org/fhir/ValueSet/characteristic-offset`)
Type	CodeableConcept
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4364. EvidenceVariable.characteristic:drugAdministration.definitionByCombination
Definition	Defines the characteristic as a combination of two or more characteristics.
Short	Used to specify how two or more characteristics are combined
Control	0..0 This element is affected by the following invariants: evv-1
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4372. EvidenceVariable.characteristic:drugAdministration.instances[x]
Definition	Number of occurrences meeting the characteristic.
Short	Number of occurrences meeting the characteristic
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4374. EvidenceVariable.characteristic:drugAdministration.duration[x]
Definition	Length of time in which the characteristic is met.
Short	Length of time in which the characteristic is met
Control	0..1
Type	Choice of: Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4376. EvidenceVariable.characteristic:drugAdministration.timeFromEvent
Definition	Timing in which the characteristic is determined.
Short	Timing in which the characteristic is determined
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4378. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4380. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4382. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4384. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.description
Definition	Human readable description.
Short	Human readable description
Control	0..1
Type	markdown
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4386. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.note
Definition	A human-readable string to clarify or explain concepts about the timeFromEvent.
Short	Used for footnotes or explanatory notes
Control	0..*
Type	Annotation
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4388. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.event[x]
Definition	The event used as a base point (reference point) in time.
Short	The event used as a base point (reference point) in time
Control	0..1
Binding	For example codes, see EvidenceVariableEvent (example to `http://hl7.org/fhir/ValueSet/evidence-variable-event`)
Type	Choice of: CodeableConcept, Reference, dateTime, id
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4390. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.quantity
Definition	Used to express the observation at a defined amount of time before or after the event.
Short	Used to express the observation at a defined amount of time before or after the event
Control	0..1
Type	Quantity
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4392. EvidenceVariable.characteristic:drugAdministration.timeFromEvent.range
Definition	Used to express the observation within a period before and/or after the event.
Short	Used to express the observation within a period before and/or after the event
Control	0..1
Type	Range
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4394. EvidenceVariable.handling
Definition	The method of handling in statistical analysis.
Short	continuous \| dichotomous \| ordinal \| polychotomous
Control	0..1
Binding	The codes SHALL be taken from EvidenceVariableHandling (required to `http://hl7.org/fhir/ValueSet/variable-handling\|5.0.0`)
Type	code
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4396. EvidenceVariable.category
Definition	A grouping for ordinal or polychotomous variables.
Short	A grouping for ordinal or polychotomous variables
Control	0..*
Type	BackboneElement
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4398. EvidenceVariable.category.id
Definition	Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.
Short	Unique id for inter-element referencing
Control	0..1 This element is affected by the following invariants: ele-1
Type	string
Is Modifier	false
XML Format	In the XML format, this property is represented as an attribute.
Summary	false
4400. EvidenceVariable.category.extension
Definition	May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.
Short	Additional content defined by implementations
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	false
Summary	false
Alternate Names	extensions, user content
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4402. EvidenceVariable.category.modifierExtension
Definition	May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions. Modifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).
Short	Extensions that cannot be ignored even if unrecognized
Comments	There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.
Control	0..*
Type	Extension
Is Modifier	true because Modifier extensions are expected to modify the meaning or interpretation of the element that contains them
Summary	true
Requirements	Modifier extensions allow for extensions that cannot be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the definition of modifier extensions.
Alternate Names	extensions, user content, modifiers
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`) ext-1: Must have either extensions or value[x], not both (`extension.exists() != value.exists()`)
4404. EvidenceVariable.category.name
Definition	Description of the grouping.
Short	Description of the grouping
Control	0..1
Type	string
Is Modifier	false
Primitive Value	This primitive element may be present, or absent, or replaced by an extension
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)
4406. EvidenceVariable.category.value[x]
Definition	Definition of the grouping.
Short	Definition of the grouping
Control	0..1
Type	Choice of: CodeableConcept, Quantity, Range
[x] Note	SeeChoice of Data Typesfor further information about how to use [x]
Is Modifier	false
Must Support	false
Summary	false
Invariants	ele-1: All FHIR elements must have a @value or children (`hasValue() or (children().count() > id.count())`)